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Overexpression of GRK2 in vascular smooth muscle leads to inappropriate hypertension and acute heart failure as in clinical scenario 1

Clinical scenario 1 (CS1) is acute heart failure (HF) characterized by transient systolic blood pressure (SBP) elevation and pulmonary congestion. Although it is managed by vasodilators, the molecular mechanism remains unclear. The sympathetic nervous system plays a key role in HF, and desensitizati...

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Detalles Bibliográficos
Autores principales: Yano, Hiroki, Onoue, Kenji, Tokinaga, Shiho, Ioka, Tomoko, Ishihara, Satomi, Hashimoto, Yukihiro, Nakada, Yasuki, Nakagawa, Hitoshi, Ueda, Tomoya, Seno, Ayako, Nishida, Taku, Watanabe, Makoto, Saito, Yoshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182096/
https://www.ncbi.nlm.nih.gov/pubmed/37173348
http://dx.doi.org/10.1038/s41598-023-34209-5