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A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease

Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder that is characterized by deficiencies in the phagocytes capacity to eliminate ingested microorganisms, which frequently causes bacterial and fungal infections. The extensive involvement of the lungs, ribs, and vertebrae...

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Autores principales: Tavakolizadeh, Nahid, Ahmadzade, Amir Mahmoud, Beizaei, Behnam, Izanlu, Mostafa, Khoroushi, Farzaneh, Aminzadeh, Behzad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182263/
https://www.ncbi.nlm.nih.gov/pubmed/37192846
http://dx.doi.org/10.1002/ccr3.7341
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author Tavakolizadeh, Nahid
Ahmadzade, Amir Mahmoud
Beizaei, Behnam
Izanlu, Mostafa
Khoroushi, Farzaneh
Aminzadeh, Behzad
author_facet Tavakolizadeh, Nahid
Ahmadzade, Amir Mahmoud
Beizaei, Behnam
Izanlu, Mostafa
Khoroushi, Farzaneh
Aminzadeh, Behzad
author_sort Tavakolizadeh, Nahid
collection PubMed
description Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder that is characterized by deficiencies in the phagocytes capacity to eliminate ingested microorganisms, which frequently causes bacterial and fungal infections. The extensive involvement of the lungs, ribs, and vertebrae that is complicated by multiple abscesses from aspergillosis is rare. in this study, we report a 13‐year‐old boy with CGD who experienced concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral, and epidural abscesses as a result of Aspergillus flavus infection with associated computed tomography scan and magnetic resonance imaging findings. Patients with CGD are susceptible to Aspergillus infection. Correct diagnosis based on clinical and paraclinical findings as well as choosing the best treatment regimen is essential for achieving a favorable outcome.
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spelling pubmed-101822632023-05-14 A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease Tavakolizadeh, Nahid Ahmadzade, Amir Mahmoud Beizaei, Behnam Izanlu, Mostafa Khoroushi, Farzaneh Aminzadeh, Behzad Clin Case Rep Case Report Chronic granulomatous disease (CGD) is a rare primary immunodeficiency disorder that is characterized by deficiencies in the phagocytes capacity to eliminate ingested microorganisms, which frequently causes bacterial and fungal infections. The extensive involvement of the lungs, ribs, and vertebrae that is complicated by multiple abscesses from aspergillosis is rare. in this study, we report a 13‐year‐old boy with CGD who experienced concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral, and epidural abscesses as a result of Aspergillus flavus infection with associated computed tomography scan and magnetic resonance imaging findings. Patients with CGD are susceptible to Aspergillus infection. Correct diagnosis based on clinical and paraclinical findings as well as choosing the best treatment regimen is essential for achieving a favorable outcome. John Wiley and Sons Inc. 2023-05-12 /pmc/articles/PMC10182263/ /pubmed/37192846 http://dx.doi.org/10.1002/ccr3.7341 Text en © 2023 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Tavakolizadeh, Nahid
Ahmadzade, Amir Mahmoud
Beizaei, Behnam
Izanlu, Mostafa
Khoroushi, Farzaneh
Aminzadeh, Behzad
A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title_full A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title_fullStr A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title_full_unstemmed A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title_short A rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
title_sort rare case of concurrent pneumonia, rib osteomyelitis, spondylodiscitis, paravertebral and epidural abscesses in a patient with chronic granulomatous disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182263/
https://www.ncbi.nlm.nih.gov/pubmed/37192846
http://dx.doi.org/10.1002/ccr3.7341
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