Spatial metabolomics reveals glycogen as an actionable target for pulmonary fibrosis

Matrix assisted laser desorption/ionization imaging has greatly improved our understanding of spatial biology, however a robust bioinformatic pipeline for data analysis is lacking. Here, we demonstrate the application of high-dimensionality reduction/spatial clustering and histopathological annotati...

Descripción completa

Detalles Bibliográficos
Autores principales: Conroy, Lindsey R., Clarke, Harrison A., Allison, Derek B., Valenca, Samuel Santos, Sun, Qi, Hawkinson, Tara R., Young, Lyndsay E. A., Ferreira, Juanita E., Hammonds, Autumn V., Dunne, Jaclyn B., McDonald, Robert J., Absher, Kimberly J., Dong, Brittany E., Bruntz, Ronald C., Markussen, Kia H., Juras, Jelena A., Alilain, Warren J., Liu, Jinze, Gentry, Matthew S., Angel, Peggi M., Waters, Christopher M., Sun, Ramon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182559/
https://www.ncbi.nlm.nih.gov/pubmed/37179348
http://dx.doi.org/10.1038/s41467-023-38437-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182559/
https://www.ncbi.nlm.nih.gov/pubmed/37179348
http://dx.doi.org/10.1038/s41467-023-38437-1

Ejemplares similares