Cargando…

Type A Thymoma with Spinal and Cranial Metastases: A Case Report

INTRODUCTION: While metastases of malignant thymomas have been shown, type A thymomas are often treated as benign. Type A thymomas often have excellent response to treatment, low recurrence rate, and a small malignant potential. To date, there have been no reports of type A thymomas with spinal meta...

Descripción completa

Detalles Bibliográficos
Autores principales: Cusano, Antonio, Wellington, Ian J, Forouhar, Faripour A, Mallozzi, Scott S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Indian Orthopaedic Research Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182573/
https://www.ncbi.nlm.nih.gov/pubmed/37193387
http://dx.doi.org/10.13107/jocr.2023.v13.i04.3620
Descripción
Sumario:INTRODUCTION: While metastases of malignant thymomas have been shown, type A thymomas are often treated as benign. Type A thymomas often have excellent response to treatment, low recurrence rate, and a small malignant potential. To date, there have been no reports of type A thymomas with spinal metastases. CASE REPORT: A 66-year-old female with a type A thymoma metastatic to the T7 and T8 vertebral bodies and brain, with associated pathologic burst fracture, collapse of T7, and significant focal kyphosis . The patient underwent successful T7–T8 posterior corpectomy and T4–T11 posterior spinal fusion. At 2 years of follow-up, she was ambulating without assistive devices and completed spinal radiation and initial chemotherapy. CONCLUSION: Metastatic type A thymoma is a rare phenomenon. While traditionally thought to have low recurrence rates and overall excellent survival rates, our case suggests that the biologic malignant potential of a type A thymoma may not be fully understood.