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Type A Thymoma with Spinal and Cranial Metastases: A Case Report
INTRODUCTION: While metastases of malignant thymomas have been shown, type A thymomas are often treated as benign. Type A thymomas often have excellent response to treatment, low recurrence rate, and a small malignant potential. To date, there have been no reports of type A thymomas with spinal meta...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Indian Orthopaedic Research Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182573/ https://www.ncbi.nlm.nih.gov/pubmed/37193387 http://dx.doi.org/10.13107/jocr.2023.v13.i04.3620 |
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author | Cusano, Antonio Wellington, Ian J Forouhar, Faripour A Mallozzi, Scott S |
author_facet | Cusano, Antonio Wellington, Ian J Forouhar, Faripour A Mallozzi, Scott S |
author_sort | Cusano, Antonio |
collection | PubMed |
description | INTRODUCTION: While metastases of malignant thymomas have been shown, type A thymomas are often treated as benign. Type A thymomas often have excellent response to treatment, low recurrence rate, and a small malignant potential. To date, there have been no reports of type A thymomas with spinal metastases. CASE REPORT: A 66-year-old female with a type A thymoma metastatic to the T7 and T8 vertebral bodies and brain, with associated pathologic burst fracture, collapse of T7, and significant focal kyphosis . The patient underwent successful T7–T8 posterior corpectomy and T4–T11 posterior spinal fusion. At 2 years of follow-up, she was ambulating without assistive devices and completed spinal radiation and initial chemotherapy. CONCLUSION: Metastatic type A thymoma is a rare phenomenon. While traditionally thought to have low recurrence rates and overall excellent survival rates, our case suggests that the biologic malignant potential of a type A thymoma may not be fully understood. |
format | Online Article Text |
id | pubmed-10182573 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Indian Orthopaedic Research Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-101825732023-05-14 Type A Thymoma with Spinal and Cranial Metastases: A Case Report Cusano, Antonio Wellington, Ian J Forouhar, Faripour A Mallozzi, Scott S J Orthop Case Rep Case Report INTRODUCTION: While metastases of malignant thymomas have been shown, type A thymomas are often treated as benign. Type A thymomas often have excellent response to treatment, low recurrence rate, and a small malignant potential. To date, there have been no reports of type A thymomas with spinal metastases. CASE REPORT: A 66-year-old female with a type A thymoma metastatic to the T7 and T8 vertebral bodies and brain, with associated pathologic burst fracture, collapse of T7, and significant focal kyphosis . The patient underwent successful T7–T8 posterior corpectomy and T4–T11 posterior spinal fusion. At 2 years of follow-up, she was ambulating without assistive devices and completed spinal radiation and initial chemotherapy. CONCLUSION: Metastatic type A thymoma is a rare phenomenon. While traditionally thought to have low recurrence rates and overall excellent survival rates, our case suggests that the biologic malignant potential of a type A thymoma may not be fully understood. Indian Orthopaedic Research Group 2023-04 2023-04 /pmc/articles/PMC10182573/ /pubmed/37193387 http://dx.doi.org/10.13107/jocr.2023.v13.i04.3620 Text en Copyright: © Indian Orthopaedic Research Group https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 Unported, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms |
spellingShingle | Case Report Cusano, Antonio Wellington, Ian J Forouhar, Faripour A Mallozzi, Scott S Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title | Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title_full | Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title_fullStr | Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title_full_unstemmed | Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title_short | Type A Thymoma with Spinal and Cranial Metastases: A Case Report |
title_sort | type a thymoma with spinal and cranial metastases: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182573/ https://www.ncbi.nlm.nih.gov/pubmed/37193387 http://dx.doi.org/10.13107/jocr.2023.v13.i04.3620 |
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