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Functional status and spatial architecture of tumor-infiltrating CD8+ T cells are associated with lymph node metastases in non-small cell lung cancer

BACKGROUND: Anti-PD-(L)1 immunotherapy has been recommended for non-small cell lung cancer (NSCLC) patients with lymph node metastases (LNM). However, the exact functional feature and spatial architecture of tumor-infiltrating CD8 + T cells remain unclear in these patients. METHODS: Tissue microarra...

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Detalles Bibliográficos
Autores principales:	Yang, Guanqun, Cai, Siqi, Hu, Mengyu, Li, Chaozhuo, Yang, Liying, Zhang, Wei, Sun, Jujie, Sun, Fenghao, Xing, Ligang, Sun, Xiaorong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182600/ https://www.ncbi.nlm.nih.gov/pubmed/37173705 http://dx.doi.org/10.1186/s12967-023-04154-y

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