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Modulating AHR function offers exciting therapeutic potential in gut immunity and inflammation

Aryl hydrocarbon receptor (AHR) is a ligand-dependent transcription factor. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a classical exogenous synthetic ligand of AHR that has significant immunotoxic effects. Activation of AHR has beneficial effects on intestinal immune responses, but inactivation...

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Detalles Bibliográficos
Autores principales: Chen, Yue, Wang, Yadong, Fu, Yawei, Yin, Yulong, Xu, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182712/
https://www.ncbi.nlm.nih.gov/pubmed/37179416
http://dx.doi.org/10.1186/s13578-023-01046-y