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Robust microtubule dynamics facilitate low-tension kinetochore detachment in metaphase

During mitosis, sister chromatids are stretched apart at their centromeres via their attachment to oppositely oriented kinetochore microtubules. This stretching generates inwardly directed tension across the separated sister centromeres. The cell leverages this tension signal to detect and then corr...

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Detalles Bibliográficos
Autores principales: Parmar, Sneha, Gonzalez, Samuel J., Heckel, Julia M., Mukherjee, Soumya, McClellan, Mark, Clarke, Duncan J., Johansson, Marnie, Tank, Damien, Geisness, Athena, Wood, David K., Gardner, Melissa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182774/
https://www.ncbi.nlm.nih.gov/pubmed/37166419
http://dx.doi.org/10.1083/jcb.202202085