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Suppression of NLRP3/Caspase-1/GSDMD Mediated Corneal Epithelium Pyroptosis Using Melatonin-Loaded Liposomes to Inhibit Benzalkonium Chloride-Induced Dry Eye Disease

INTRODUCTION: Benzalkonium chloride (BAC) is widely employed as a preservative in eye drops, which will cause the death of corneal epithelial cells due to ROS production, DNA strand breakage, and mitochondrial dysfunction, resulting in dry eye disease (DED)-like changes in ocular surface tissues. In...

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Detalles Bibliográficos
Autores principales:	Lou, Qi, Pan, Lu, Xiang, Shengjin, Li, Yueting, Jin, Jiahui, Tan, Jingyang, Huang, Baoshan, Nan, Kaihui, Lin, Sen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182801/ https://www.ncbi.nlm.nih.gov/pubmed/37192892 http://dx.doi.org/10.2147/IJN.S403337

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