Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report

Vitiligo is an idiopathic skin disorder of multifactorial etiology that is characterized by skin depigmentation. Generalized vitiligo following radiation therapy has rarely been reported in the literature. The mechanism underlying radiation-induced disseminated vitiligo is not yet fully understood....

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Detalles Bibliográficos
Autores principales: Sirody, Jordin, Orlinsky, Diane, Simmons-O’Brien, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Dermatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182855/
https://www.ncbi.nlm.nih.gov/pubmed/37193461
http://dx.doi.org/10.7759/cureus.37538
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author Sirody, Jordin
Orlinsky, Diane
Simmons-O’Brien, Eva
author_facet Sirody, Jordin
Orlinsky, Diane
Simmons-O’Brien, Eva
author_sort Sirody, Jordin
collection PubMed
description Vitiligo is an idiopathic skin disorder of multifactorial etiology that is characterized by skin depigmentation. Generalized vitiligo following radiation therapy has rarely been reported in the literature. The mechanism underlying radiation-induced disseminated vitiligo is not yet fully understood. However, multiple factors, including genetic susceptibility and autoimmunity, are likely involved in the pathogenesis of the condition. We report a case of disseminated vitiligo in a patient with no preexisting personal or family history of the condition following three months of localized radiation therapy to the mediastinum.
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spelling pubmed-101828552023-05-14 Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report Sirody, Jordin Orlinsky, Diane Simmons-O’Brien, Eva Cureus Dermatology Vitiligo is an idiopathic skin disorder of multifactorial etiology that is characterized by skin depigmentation. Generalized vitiligo following radiation therapy has rarely been reported in the literature. The mechanism underlying radiation-induced disseminated vitiligo is not yet fully understood. However, multiple factors, including genetic susceptibility and autoimmunity, are likely involved in the pathogenesis of the condition. We report a case of disseminated vitiligo in a patient with no preexisting personal or family history of the condition following three months of localized radiation therapy to the mediastinum. Cureus 2023-04-13 /pmc/articles/PMC10182855/ /pubmed/37193461 http://dx.doi.org/10.7759/cureus.37538 Text en Copyright © 2023, Sirody et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Sirody, Jordin
Orlinsky, Diane
Simmons-O’Brien, Eva
Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title_full Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title_fullStr Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title_full_unstemmed Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title_short Generalized Vitiligo Following Radiation Therapy for a B2 Thymoma: A Case Report
title_sort generalized vitiligo following radiation therapy for a b2 thymoma: a case report
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182855/
https://www.ncbi.nlm.nih.gov/pubmed/37193461
http://dx.doi.org/10.7759/cureus.37538
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AT orlinskydiane generalizedvitiligofollowingradiationtherapyforab2thymomaacasereport
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