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Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior

Phyllodes tumors are uncommon biphasic breast tumors with a wide range of clinical behaviors. The distinction between a phyllodes tumor and a fibroadenoma can be difficult. The diagnosis of phyllodes tumor should be suspected in all women who present with a rapidly growing breast lump. Based on the...

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Autores principales: Tomé, Ana Isabel, Figueiredo, Joana, Antunes, Sofia Carralas, Trindade, Madalena, Travancinha, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182856/
https://www.ncbi.nlm.nih.gov/pubmed/37193421
http://dx.doi.org/10.7759/cureus.37537
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author Tomé, Ana Isabel
Figueiredo, Joana
Antunes, Sofia Carralas
Trindade, Madalena
Travancinha, Daniel
author_facet Tomé, Ana Isabel
Figueiredo, Joana
Antunes, Sofia Carralas
Trindade, Madalena
Travancinha, Daniel
author_sort Tomé, Ana Isabel
collection PubMed
description Phyllodes tumors are uncommon biphasic breast tumors with a wide range of clinical behaviors. The distinction between a phyllodes tumor and a fibroadenoma can be difficult. The diagnosis of phyllodes tumor should be suspected in all women who present with a rapidly growing breast lump. Based on the histological characteristics, the World Health Organization (WHO) classifies phyllodes tumors as benign, borderline, or malignant. The risk of recurrence and metastatic potential varies based on histological features. Wide excision or mastectomy is the standard of care ensuring histologically clear margins. Despite the grading criteria defined by the WHO, the management of phyllodes tumors continues to be a challenge. We report the case of a 48-year-old woman who presented to the emergency department with a large and ulcerated phyllodes tumor of the left breast. The tumor size did not allow conservative surgery. The final diagnosis of a borderline phyllodes tumor was made, and, in this case, the patient did not undergo adjuvant treatment.
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spelling pubmed-101828562023-05-14 Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior Tomé, Ana Isabel Figueiredo, Joana Antunes, Sofia Carralas Trindade, Madalena Travancinha, Daniel Cureus Obstetrics/Gynecology Phyllodes tumors are uncommon biphasic breast tumors with a wide range of clinical behaviors. The distinction between a phyllodes tumor and a fibroadenoma can be difficult. The diagnosis of phyllodes tumor should be suspected in all women who present with a rapidly growing breast lump. Based on the histological characteristics, the World Health Organization (WHO) classifies phyllodes tumors as benign, borderline, or malignant. The risk of recurrence and metastatic potential varies based on histological features. Wide excision or mastectomy is the standard of care ensuring histologically clear margins. Despite the grading criteria defined by the WHO, the management of phyllodes tumors continues to be a challenge. We report the case of a 48-year-old woman who presented to the emergency department with a large and ulcerated phyllodes tumor of the left breast. The tumor size did not allow conservative surgery. The final diagnosis of a borderline phyllodes tumor was made, and, in this case, the patient did not undergo adjuvant treatment. Cureus 2023-04-13 /pmc/articles/PMC10182856/ /pubmed/37193421 http://dx.doi.org/10.7759/cureus.37537 Text en Copyright © 2023, Tomé et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Obstetrics/Gynecology
Tomé, Ana Isabel
Figueiredo, Joana
Antunes, Sofia Carralas
Trindade, Madalena
Travancinha, Daniel
Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title_full Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title_fullStr Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title_full_unstemmed Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title_short Breast Phyllodes Tumor: A Tumor With Unpredictable Clinical Behavior
title_sort breast phyllodes tumor: a tumor with unpredictable clinical behavior
topic Obstetrics/Gynecology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10182856/
https://www.ncbi.nlm.nih.gov/pubmed/37193421
http://dx.doi.org/10.7759/cureus.37537
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