The ancestral haplotype markers HLA -A3 and B7 do not influence the likelihood of advanced hepatic fibrosis or cirrhosis in HFE hemochromatosis

Advanced hepatic fibrosis occurs in up to 25% of individuals with C282Y homozygous hemochromatosis. Our aim was to determine whether human leukocyte antigen (HLA)-A3 and B7 alleles act as genetic modifiers of the likelihood of advanced hepatic fibrosis. Between 1972 and 2013, 133 HFE C282Y homozygou...

Descripción completa

Detalles Bibliográficos
Autores principales: Olynyk, John K., Grainger, Richard, Currie, Helen, Ramm, Louise E., Ramm, Grant A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183001/
https://www.ncbi.nlm.nih.gov/pubmed/37179448
http://dx.doi.org/10.1038/s41598-023-35028-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183001/
https://www.ncbi.nlm.nih.gov/pubmed/37179448
http://dx.doi.org/10.1038/s41598-023-35028-4

Ejemplares similares