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Blocking muscle wasting via deletion of the muscle-specific E3 ligase MuRF1 impedes pancreatic tumor growth

Cancer-induced muscle wasting reduces quality of life, complicates or precludes cancer treatments, and predicts early mortality. Herein, we investigate the requirement of the muscle-specific E3 ubiquitin ligase, MuRF1, for muscle wasting induced by pancreatic cancer. Murine pancreatic cancer (KPC) c...

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Detalles Bibliográficos
Autores principales:	Neyroud, Daria, Laitano, Orlando, Dasgupta, Aneesha, Lopez, Christopher, Schmitt, Rebecca E., Schneider, Jessica Z., Hammers, David W., Sweeney, H. Lee, Walter, Glenn A., Doles, Jason, Judge, Sarah M., Judge, Andrew R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183033/ https://www.ncbi.nlm.nih.gov/pubmed/37179425 http://dx.doi.org/10.1038/s42003-023-04902-2

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