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Endothelial cell-derived stem cell factor promotes lipid accumulation through c-Kit-mediated increase of lipogenic enzymes in brown adipocytes

Active thermogenesis in the brown adipose tissue (BAT) facilitating the utilization of lipids and glucose is critical for maintaining body temperature and reducing metabolic diseases, whereas inactive BAT accumulates lipids in brown adipocytes (BAs), leading to BAT whitening. Although cellular cross...

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Detalles Bibliográficos
Autores principales: Lee, Hyuek Jong, Lee, Jueun, Yang, Myung Jin, Kim, Young-Chan, Hong, Seon Pyo, Kim, Jung Mo, Hwang, Geum-Sook, Koh, Gou Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183046/
https://www.ncbi.nlm.nih.gov/pubmed/37179330
http://dx.doi.org/10.1038/s41467-023-38433-5