Cargando…

m(6)A eraser ALKBH5 mitigates the apoptosis of cardiomyocytes in ischemia reperfusion injury through m(6)A/SIRT1 axis

Recent studies have shown that the potential regulatory role of N(6)-methyladenine (m(6)A) modification may affect the occurrence and development of various cardiovascular diseases. However, the regulatory mechanism of m(6)A modification on myocardial ischemia reperfusion injury (MIRI) is rarely rep...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Liangliang, Liu, Zhen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2023
Materias:	Biochemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183170/ https://www.ncbi.nlm.nih.gov/pubmed/37193033 http://dx.doi.org/10.7717/peerj.15269

Ejemplares similares

Gene Polymorphisms of m6A Erasers FTO and ALKBH1 Associated with Susceptibility to Gastric Cancer
por: Li, Yue, et al.
Publicado: (2022)

Downregulated ALKBH5 contributes to myocardial ischemia/reperfusion injury by increasing m(6)A modification of Trio mRNA
por: Li, Jiaxin, et al.
Publicado: (2022)

Epigenetic modification mechanism of histone demethylase KDM1A in regulating cardiomyocyte apoptosis after myocardial ischemia-reperfusion injury
por: He, Lin, et al.
Publicado: (2022)

m(6)A reader IGF2BP1 accelerates apoptosis of high glucose-induced vascular endothelial cells in a m(6)A-HMGB1 dependent manner
por: Liang, Anru, et al.
Publicado: (2023)

m(6)A demethylase FTO regulates the apoptosis and inflammation of cardiomyocytes via YAP1 in ischemia-reperfusion injury
por: Ke, Wei-Liang, et al.
Publicado: (2022)

Taxifolin protects rat against myocardial ischemia/reperfusion injury by modulating the mitochondrial apoptosis pathway
por: Tang, Zhenqiu, et al.
Publicado: (2019)

Identification of ‘erasers’ for lysine crotonylated histone marks using a chemical proteomics approach
por: Bao, Xiucong, et al.
Publicado: (2014)

N(6)-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury
por: Xu, Kaiwei, et al.
Publicado: (2020)

Role of m6A writers, erasers and readers in cancer
por: Fang, Zhen, et al.
Publicado: (2022)

The detection and functions of RNA modification m(6)A based on m(6)A writers and erasers
por: Zhang, Wei, et al.
Publicado: (2021)

Identification and Characterization of a Glucometabolic Prognostic Gene Signature in Neuroblastoma based on N6-methyladenosine Eraser ALKBH5
por: Tan, Kezhe, et al.
Publicado: (2022)

Structural insights into the molecular mechanism of the m(6)A writer complex
por: Śledź, Paweł, et al.
Publicado: (2016)

Altered expression profile of glycolytic enzymes during testicular ischemia reperfusion injury is associated with the p53/TIGAR pathway: effect of fructose 1,6-diphosphate
por: Al-Maghrebi, May, et al.
Publicado: (2016)

Relationship between ferroptosis and mitophagy in cardiac ischemia reperfusion injury: a mini-review
por: Liu, Cuihua, et al.
Publicado: (2023)

SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
por: Zhang, Xiaoyu, et al.
Publicado: (2017)

Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
por: Zhang, Xiong, et al.
Publicado: (2020)

Ferroptotic cardiomyocyte-derived exosomes promote cardiac macrophage M1 polarization during myocardial infarction
por: Sun, Shengjia, et al.
Publicado: (2022)

Mammalian ALKBH1 serves as an N(6)-mA demethylase of unpairing DNA
por: Zhang, Min, et al.
Publicado: (2020)

N(6)-methyladenosine (m(6)A) reader IGF2BP1 facilitates clear-cell renal cell carcinoma aerobic glycolysis
por: Yuan, Bao, et al.
Publicado: (2023)

Deregulation of N6-Methyladenosine RNA Modification and Its Erasers FTO/ALKBH5 among the Main Renal Cell Tumor Subtypes
por: Guimarães-Teixeira, Catarina, et al.
Publicado: (2021)

Retraction: Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
Publicado: (2022)

METTL3 and ALKBH5 oppositely regulate m(6)A modification of TFEB mRNA, which dictates the fate of hypoxia/reoxygenation-treated cardiomyocytes
por: Song, Huiwen, et al.
Publicado: (2019)

N(6)-methyladenosine (m(6)A) methylation in ischemia–reperfusion injury
por: Yao, Weifeng, et al.
Publicado: (2020)

Splice site m(6)A methylation prevents binding of DGCR8 to suppress KRT4 pre-mRNA splicing in oral squamous cell carcinoma
por: Li, Xiaoxu, et al.
Publicado: (2023)

N(6)-methyladenosine reader YTHDF1 regulates the proliferation and migration of airway smooth muscle cells through m(6)A/cyclin D1 in asthma
por: Wang, Juan, et al.
Publicado: (2023)

Predict Epitranscriptome Targets and Regulatory Functions of N(6)-Methyladenosine (m(6)A) Writers and Erasers
por: Song, Yiyou, et al.
Publicado: (2019)

Comprehensive Analysis of N6-Methyladenosine (m6A) Writers, Erasers, and Readers in Cervical Cancer
por: Condic, Mateja, et al.
Publicado: (2022)

ALKBH5 regulates cardiomyocyte proliferation and heart regeneration by demethylating the mRNA of YTHDF1
por: Han, Zhenbo, et al.
Publicado: (2021)

Expression of Concern: Dexmedetomidine postconditioning suppresses myocardial ischemia/reperfusion injury by activating the SIRT1/mTOR axis
Publicado: (2022)

ALKBH5-mediated m(6)A demethylation of FOXM1 mRNA promotes progression of uveal melanoma
por: Hao, Lili, et al.
Publicado: (2021)

Effects of procyanidin on cardiomyocyte apoptosis after myocardial ischemia reperfusion in rats
por: Liu, Dan
Publicado: (2018)

Treatment with sodium (S)-2-hydroxyglutarate prevents liver injury in an ischemia-reperfusion model in female Wistar rats
por: Cienfuegos-Pecina, Eduardo, et al.
Publicado: (2021)

Comprehensive immunohistochemical analysis of N6-methyladenosine (m6A) writers, erasers, and readers in endometrial cancer
por: Ralser, Damian J., et al.
Publicado: (2022)

RNA m(6)A demethylase ALKBH5 regulates the development of γδ T cells
por: Ding, Chenbo, et al.
Publicado: (2022)

Melatonin ameliorates myocardial injury by reducing apoptosis and autophagy of cardiomyocytes in a rat cardiopulmonary bypass model
por: Huang, Xiaolin, et al.
Publicado: (2021)

Suxiao Jiuxin Pill alleviates myocardial ischemia–reperfusion injury through the ALKBH5/GSK3β/mTOR pathway
por: Li, Yiping, et al.
Publicado: (2023)

Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice
por: Ghosh, Shrestha, et al.
Publicado: (2018)

Effects of writers, erasers and readers within miRNA‐related m6A modification in cancers
por: Feng, Huiru, et al.
Publicado: (2022)

HOTAIR regulates SIRT3-mediated cardiomyocyte survival after myocardial ischemia/reperfusion by interacting with FUS
por: Liu, Jixuan, et al.
Publicado: (2023)

N-acetyl-L-tryptophan attenuates hepatic ischemia-reperfusion injury via regulating TLR4/NLRP3 signaling pathway in rats
por: Pan, Yitong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_kq7ml7hq9srvetgj81pqbtdr5t