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To Bleed or Not to Bleed

The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Mel...

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Autores principales: Iskander, Peter A, Zaidi, Syed Muhammad Hussain, Zheng, Jiayi, Iskander, Anthony, Aloysius, Mark M, Khurana, Vikas, Nasr, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183236/
https://www.ncbi.nlm.nih.gov/pubmed/37193446
http://dx.doi.org/10.7759/cureus.37591
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author Iskander, Peter A
Zaidi, Syed Muhammad Hussain
Zheng, Jiayi
Iskander, Anthony
Aloysius, Mark M
Khurana, Vikas
Nasr, Simin
author_facet Iskander, Peter A
Zaidi, Syed Muhammad Hussain
Zheng, Jiayi
Iskander, Anthony
Aloysius, Mark M
Khurana, Vikas
Nasr, Simin
author_sort Iskander, Peter A
collection PubMed
description The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Melenic or “tar-colored” bowel movements are more likely to occur from upper bleeds as the color is secondary to digestion of hemoglobin as it passes through the GI tract. At times, there can be a mix of the two which can make a clinical decision for intervention less obvious. To make matters more difficult, some of these patients can be on anticoagulation therapy for a myriad of reasons. Risks versus benefits at these times need to be weighed as holding this therapy may make the patients more prone to clotting while continuation would increase likelihood of bleeding. We present a case of a hypercoagulable patient who was started on rivaroxaban for history of pulmonary embolism; this led to the onset of an acute GI bleed from a duodenal diverticulum requiring endoscopic intervention. Although this can be a known effect of the therapy, the severity of bleed and changes in hemodynamics can warrant very different management strategies. 
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spelling pubmed-101832362023-05-15 To Bleed or Not to Bleed Iskander, Peter A Zaidi, Syed Muhammad Hussain Zheng, Jiayi Iskander, Anthony Aloysius, Mark M Khurana, Vikas Nasr, Simin Cureus Internal Medicine The location of gastrointestinal (GI) bleeding can be characterized based on the characteristics of the bowel movements these patients present with. Bright red blood per rectum is usually associated with a lower bleed; if brisk and significant enough, however, upper bleeds can present similarly. Melenic or “tar-colored” bowel movements are more likely to occur from upper bleeds as the color is secondary to digestion of hemoglobin as it passes through the GI tract. At times, there can be a mix of the two which can make a clinical decision for intervention less obvious. To make matters more difficult, some of these patients can be on anticoagulation therapy for a myriad of reasons. Risks versus benefits at these times need to be weighed as holding this therapy may make the patients more prone to clotting while continuation would increase likelihood of bleeding. We present a case of a hypercoagulable patient who was started on rivaroxaban for history of pulmonary embolism; this led to the onset of an acute GI bleed from a duodenal diverticulum requiring endoscopic intervention. Although this can be a known effect of the therapy, the severity of bleed and changes in hemodynamics can warrant very different management strategies.  Cureus 2023-04-14 /pmc/articles/PMC10183236/ /pubmed/37193446 http://dx.doi.org/10.7759/cureus.37591 Text en Copyright © 2023, Iskander et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Iskander, Peter A
Zaidi, Syed Muhammad Hussain
Zheng, Jiayi
Iskander, Anthony
Aloysius, Mark M
Khurana, Vikas
Nasr, Simin
To Bleed or Not to Bleed
title To Bleed or Not to Bleed
title_full To Bleed or Not to Bleed
title_fullStr To Bleed or Not to Bleed
title_full_unstemmed To Bleed or Not to Bleed
title_short To Bleed or Not to Bleed
title_sort to bleed or not to bleed
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183236/
https://www.ncbi.nlm.nih.gov/pubmed/37193446
http://dx.doi.org/10.7759/cureus.37591
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