CRISPR-cas9 screening identified lethal genes enriched in Hippo kinase pathway and of predictive significance in primary low-grade glioma

BACKGROUND: Low-grade gliomas (LGG) are a type of brain tumor that can be lethal, and it is essential to identify genes that are correlated with patient prognosis. In this study, we aimed to use CRISPR-cas9 screening data to identify key signaling pathways and develop a genetic signature associated...

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Detalles Bibliográficos
Autores principales: Mijiti, Maimaitili, Maimaiti, Aierpati, Chen, Xiaoqing, Tuersun, Maidina, Dilixiati, Miershayiti, Dilixiati, Yilidanna, Zhu, Guohua, Wu, Hao, Li, Yandong, Turhon, Mirzat, Abulaiti, Aimitaji, Maimaitiaili, Nuerailijiang, Yiming, Nadire, Kasimu, Maimaitijiang, Wang, Yongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183247/
https://www.ncbi.nlm.nih.gov/pubmed/37183261
http://dx.doi.org/10.1186/s10020-023-00652-3

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