Lacosamide Intoxication-induced Wide QRS Tachycardia Successfully Treated with Veno-arterial Extracorporeal Membrane Oxygenation

Lacosamide is an antiepileptic drug that acts on voltage-gated sodium channels and was approved as an antiepileptic by the Food and Drug Administration in 2008. Although the efficacy and safety of lacosamide have been established in many previous trials, some case reports have shown that it may lead...

Descripción completa

Detalles Bibliográficos
Autores principales: Takai, Chihiro, Misumi, Kayo, Kaito, Daiki, Nishida, Hiroaki, Yoshii, Masami, Yamada, So, Kobayashi, Takaomi, Koinuma, Toshitaka, Kadoya, Takashi, Kimura, Takuya, Hagiwara, Yoshihiro, Ogura, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183285/
https://www.ncbi.nlm.nih.gov/pubmed/36104195
http://dx.doi.org/10.2169/internalmedicine.0145-22
Descripción
Sumario:Lacosamide is an antiepileptic drug that acts on voltage-gated sodium channels and was approved as an antiepileptic by the Food and Drug Administration in 2008. Although the efficacy and safety of lacosamide have been established in many previous trials, some case reports have shown that it may lead to cardiovascular side effects, especially in patients with electrical conduction system disorders. We herein report a case of life-threatening cardiac arrhythmia caused by lacosamide intoxication that was successfully treated with veno-arterial extracorporeal membrane oxygenation.

Ejemplares similares