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Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis

BACKGROUND: The current study considers a new direction of surgical treatment of liver echinococcosis - the use of minimally invasive treatment methods of parasitic cysts. METHODS: After clinical and morphological substantiation of the very possibility of carrying out such procedures, 9 microwave ab...

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Autores principales: Shabunin, Alexey, Karpov, Alexey, Bedin, Vladimir, Tavobilov, Mikhail, Checenin, Grigory, Lebedev, Sergey, Ivanova, Natalya, Malishev, Anatoliy, Aladin, Mark, Abramov, Kirill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tehran University of Medical Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183441/
https://www.ncbi.nlm.nih.gov/pubmed/37197072
http://dx.doi.org/10.18502/ijpa.v18i1.12380
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author Shabunin, Alexey
Karpov, Alexey
Bedin, Vladimir
Tavobilov, Mikhail
Checenin, Grigory
Lebedev, Sergey
Ivanova, Natalya
Malishev, Anatoliy
Aladin, Mark
Abramov, Kirill
author_facet Shabunin, Alexey
Karpov, Alexey
Bedin, Vladimir
Tavobilov, Mikhail
Checenin, Grigory
Lebedev, Sergey
Ivanova, Natalya
Malishev, Anatoliy
Aladin, Mark
Abramov, Kirill
author_sort Shabunin, Alexey
collection PubMed
description BACKGROUND: The current study considers a new direction of surgical treatment of liver echinococcosis - the use of minimally invasive treatment methods of parasitic cysts. METHODS: After clinical and morphological substantiation of the very possibility of carrying out such procedures, 9 microwave ablations (MWA) and 3 radiofrequency ablations (RFA) of cysts were performed in patients with liver echinococcosis from 2017 to 2021 in the surgical clinic of Botkin Hospital, Moscow, Russia. A comparative analysis of treatment results of patients with echinococcal liver cysts (12 patients who underwent “percutaneous puncture, aspiration, injection and reaspiration” (PAIR) procedure and 12 patients – MWA and RFA) was carried out. RESULTS: The number of complications according to Clavien-Dindo classification was as follows: 8 after PAIR procedure, 3 after RFA and 3 after MWA. The median hospital length of stay (LOS) after PAIR procedure was 6.46 days versus 4.7 and 4 in the groups of patients who underwent RF and MW ablation, respectively. The frequency of relapses within the first year after PAIR procedure was 25%. The patients who underwent ablation procedures had no relapses of liver echinococcosis during observation. CONCLUSION: The presented clinical and morphological substantiation and the experience of using various types of ablation techniques on echinococcal cysts, as well as a comparative analysis with a commonly used PAIR treatment method, demonstrated the safety of RFA and MWA for the patient and efficacy in relation to the hydatid process.
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spelling pubmed-101834412023-05-16 Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis Shabunin, Alexey Karpov, Alexey Bedin, Vladimir Tavobilov, Mikhail Checenin, Grigory Lebedev, Sergey Ivanova, Natalya Malishev, Anatoliy Aladin, Mark Abramov, Kirill Iran J Parasitol Original Article BACKGROUND: The current study considers a new direction of surgical treatment of liver echinococcosis - the use of minimally invasive treatment methods of parasitic cysts. METHODS: After clinical and morphological substantiation of the very possibility of carrying out such procedures, 9 microwave ablations (MWA) and 3 radiofrequency ablations (RFA) of cysts were performed in patients with liver echinococcosis from 2017 to 2021 in the surgical clinic of Botkin Hospital, Moscow, Russia. A comparative analysis of treatment results of patients with echinococcal liver cysts (12 patients who underwent “percutaneous puncture, aspiration, injection and reaspiration” (PAIR) procedure and 12 patients – MWA and RFA) was carried out. RESULTS: The number of complications according to Clavien-Dindo classification was as follows: 8 after PAIR procedure, 3 after RFA and 3 after MWA. The median hospital length of stay (LOS) after PAIR procedure was 6.46 days versus 4.7 and 4 in the groups of patients who underwent RF and MW ablation, respectively. The frequency of relapses within the first year after PAIR procedure was 25%. The patients who underwent ablation procedures had no relapses of liver echinococcosis during observation. CONCLUSION: The presented clinical and morphological substantiation and the experience of using various types of ablation techniques on echinococcal cysts, as well as a comparative analysis with a commonly used PAIR treatment method, demonstrated the safety of RFA and MWA for the patient and efficacy in relation to the hydatid process. Tehran University of Medical Sciences 2023 /pmc/articles/PMC10183441/ /pubmed/37197072 http://dx.doi.org/10.18502/ijpa.v18i1.12380 Text en Copyright © 2023 Shabunin et al. Published by Tehran University of Medical Sciences https://creativecommons.org/licenses/by-nc/4.0/This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license (https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.
spellingShingle Original Article
Shabunin, Alexey
Karpov, Alexey
Bedin, Vladimir
Tavobilov, Mikhail
Checenin, Grigory
Lebedev, Sergey
Ivanova, Natalya
Malishev, Anatoliy
Aladin, Mark
Abramov, Kirill
Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title_full Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title_fullStr Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title_full_unstemmed Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title_short Clinical, Morphological Justification and First Experience in the Use of Radiofrequency as Well as Microwave Ablation Treatment Methods of Liver Echinococcosis
title_sort clinical, morphological justification and first experience in the use of radiofrequency as well as microwave ablation treatment methods of liver echinococcosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183441/
https://www.ncbi.nlm.nih.gov/pubmed/37197072
http://dx.doi.org/10.18502/ijpa.v18i1.12380
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