Cargando…
Effects of the Rho GTPase‐activating toxin CNF1 on fibroblasts derived from Rett syndrome patients: A pilot study
The bacterial product CNF1, through its action on the Rho GTPases, is emerging as a modulator of crucial signalling pathways involved in selected neurological diseases characterized by mitochondrial dysfunctions. Mitochondrial impairment has been hypothesized to have a key role in paramount mechanis...
Autores principales: | Cittadini, Camilla, Germinario, Elena Angela Pia, Maroccia, Zaira, Cosentino, Livia, Maselli, Valeria, Gambardella, Lucrezia, Giambenedetti, Massimo, Guidotti, Marco, Travaglione, Sara, Fallerini, Chiara, Renieri, Alessandra, Marcillo, David Israel Escobar, Ricceri, Laura, Fortini, Paola, De Filippis, Bianca, Fiorentini, Carla, Fabbri, Alessia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183712/ https://www.ncbi.nlm.nih.gov/pubmed/37078409 http://dx.doi.org/10.1111/jcmm.17624 |
Ejemplares similares
-
The Bacterial Protein CNF1 as a Potential Therapeutic Strategy against Mitochondrial Diseases: A Pilot Study
por: Fabbri, Alessia, et al.
Publicado: (2018) -
The Bacterial Toxin CNF1 Protects Human Neuroblastoma SH-SY5Y Cells against 6-Hydroxydopamine-Induced Cell Damage: The Hypothesis of CNF1-Promoted Autophagy as an Antioxidant Strategy
por: Travaglione, Sara, et al.
Publicado: (2020) -
Cnf1 Variants Endowed with the Ability to Cross the Blood–Brain Barrier: A New Potential Therapeutic Strategy for Glioblastoma
por: Colarusso, Andrea, et al.
Publicado: (2020) -
Treatment with the Bacterial Toxin CNF1 Selectively Rescues Cognitive and Brain Mitochondrial Deficits in a Female Mouse Model of Rett Syndrome Carrying a MeCP2-Null Mutation
por: Urbinati, Chiara, et al.
Publicado: (2021) -
Gut Microbiota and Colon Cancer: A Role for Bacterial Protein Toxins?
por: Fiorentini, Carla, et al.
Publicado: (2020)