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Decoding the microbial universe with metagenomics: a brief insight

A major part of any biological system on earth involves microorganisms, of which the majority are yet to be cultured. The conventional methods of culturing microbes have given fruitful outcomes yet have limitations. The curiosity for better understanding has led to the development of culture-indepen...

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Autores principales: Chaudhari, Hiral G., Prajapati, Shobha, Wardah, Zuhour Hussein, Raol, Gopal, Prajapati, Vimalkumar, Patel, Rajesh, Shati, Ali A., Alfaifi, Mohammad Y., Elbehairi, Serag Eldin I., Sayyed, R. Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183756/
https://www.ncbi.nlm.nih.gov/pubmed/37197021
http://dx.doi.org/10.3389/fgene.2023.1119740
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author Chaudhari, Hiral G.
Prajapati, Shobha
Wardah, Zuhour Hussein
Raol, Gopal
Prajapati, Vimalkumar
Patel, Rajesh
Shati, Ali A.
Alfaifi, Mohammad Y.
Elbehairi, Serag Eldin I.
Sayyed, R. Z.
author_facet Chaudhari, Hiral G.
Prajapati, Shobha
Wardah, Zuhour Hussein
Raol, Gopal
Prajapati, Vimalkumar
Patel, Rajesh
Shati, Ali A.
Alfaifi, Mohammad Y.
Elbehairi, Serag Eldin I.
Sayyed, R. Z.
author_sort Chaudhari, Hiral G.
collection PubMed
description A major part of any biological system on earth involves microorganisms, of which the majority are yet to be cultured. The conventional methods of culturing microbes have given fruitful outcomes yet have limitations. The curiosity for better understanding has led to the development of culture-independent molecular methods that help push aside the roadblocks of earlier methods. Metagenomics unifies the scientific community in search of a better understanding of the functioning of the ecosystem and its component organisms. This approach has opened a new paradigm in advanced research. It has brought to light the vast diversity and novelty among microbial communities and their genomes. This review focuses on the development of this field over time, the techniques and analysis of data generated through sequencing platforms, and its prominent interpretation and representation.
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spelling pubmed-101837562023-05-16 Decoding the microbial universe with metagenomics: a brief insight Chaudhari, Hiral G. Prajapati, Shobha Wardah, Zuhour Hussein Raol, Gopal Prajapati, Vimalkumar Patel, Rajesh Shati, Ali A. Alfaifi, Mohammad Y. Elbehairi, Serag Eldin I. Sayyed, R. Z. Front Genet Genetics A major part of any biological system on earth involves microorganisms, of which the majority are yet to be cultured. The conventional methods of culturing microbes have given fruitful outcomes yet have limitations. The curiosity for better understanding has led to the development of culture-independent molecular methods that help push aside the roadblocks of earlier methods. Metagenomics unifies the scientific community in search of a better understanding of the functioning of the ecosystem and its component organisms. This approach has opened a new paradigm in advanced research. It has brought to light the vast diversity and novelty among microbial communities and their genomes. This review focuses on the development of this field over time, the techniques and analysis of data generated through sequencing platforms, and its prominent interpretation and representation. Frontiers Media S.A. 2023-04-24 /pmc/articles/PMC10183756/ /pubmed/37197021 http://dx.doi.org/10.3389/fgene.2023.1119740 Text en Copyright © 2023 Chaudhari, Prajapati, Wardah, Raol, Prajapati, Patel, Shati, Alfaifi, Elbehairi and Sayyed. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Genetics
Chaudhari, Hiral G.
Prajapati, Shobha
Wardah, Zuhour Hussein
Raol, Gopal
Prajapati, Vimalkumar
Patel, Rajesh
Shati, Ali A.
Alfaifi, Mohammad Y.
Elbehairi, Serag Eldin I.
Sayyed, R. Z.
Decoding the microbial universe with metagenomics: a brief insight
title Decoding the microbial universe with metagenomics: a brief insight
title_full Decoding the microbial universe with metagenomics: a brief insight
title_fullStr Decoding the microbial universe with metagenomics: a brief insight
title_full_unstemmed Decoding the microbial universe with metagenomics: a brief insight
title_short Decoding the microbial universe with metagenomics: a brief insight
title_sort decoding the microbial universe with metagenomics: a brief insight
topic Genetics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183756/
https://www.ncbi.nlm.nih.gov/pubmed/37197021
http://dx.doi.org/10.3389/fgene.2023.1119740
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