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Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial

OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel...

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Autores principales: Jenabi, Ensiyeh, Khazaei, Salman, Aghababaei, Soodabeh, Moradkhani, Shirin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Menopause 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183764/
https://www.ncbi.nlm.nih.gov/pubmed/37160299
http://dx.doi.org/10.6118/jmm.22026
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author Jenabi, Ensiyeh
Khazaei, Salman
Aghababaei, Soodabeh
Moradkhani, Shirin
author_facet Jenabi, Ensiyeh
Khazaei, Salman
Aghababaei, Soodabeh
Moradkhani, Shirin
author_sort Jenabi, Ensiyeh
collection PubMed
description OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel-valerian extract or control. One 500 mg fennel-valerian extract capsule was given twice, daily for 8 weeks. The 500 mg oral placebo capsule (starch) was given the same way. RESULTS: The mean duration of hot flashes increased in both the groups over time (P < 0.001). The mean frequency and severity of hot flashes in the intervention group were significantly lower than in the control group, in the first and second months after intervention (P < 0.050). Women in the fennel-valerian extract group had a significantly lower Pittsburgh Sleep Quality Index score than the control group 2 months after intervention (P = 0.030). CONCLUSIONS: This study found that fennel-valerian extract was effective for relieving sleep disorders as well as the severity and frequency of hot flashes compared with a placebo.
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spelling pubmed-101837642023-05-16 Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial Jenabi, Ensiyeh Khazaei, Salman Aghababaei, Soodabeh Moradkhani, Shirin J Menopausal Med Original Article OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel-valerian extract or control. One 500 mg fennel-valerian extract capsule was given twice, daily for 8 weeks. The 500 mg oral placebo capsule (starch) was given the same way. RESULTS: The mean duration of hot flashes increased in both the groups over time (P < 0.001). The mean frequency and severity of hot flashes in the intervention group were significantly lower than in the control group, in the first and second months after intervention (P < 0.050). Women in the fennel-valerian extract group had a significantly lower Pittsburgh Sleep Quality Index score than the control group 2 months after intervention (P = 0.030). CONCLUSIONS: This study found that fennel-valerian extract was effective for relieving sleep disorders as well as the severity and frequency of hot flashes compared with a placebo. The Korean Society of Menopause 2023-04 2023-04-28 /pmc/articles/PMC10183764/ /pubmed/37160299 http://dx.doi.org/10.6118/jmm.22026 Text en Copyright © by The Korean Society of Menopause https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ).
spellingShingle Original Article
Jenabi, Ensiyeh
Khazaei, Salman
Aghababaei, Soodabeh
Moradkhani, Shirin
Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title_full Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title_fullStr Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title_full_unstemmed Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title_short Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
title_sort effect of fennel-valerian extract on hot flashes and sleep disorders in postmenopausal women: a randomized trial
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183764/
https://www.ncbi.nlm.nih.gov/pubmed/37160299
http://dx.doi.org/10.6118/jmm.22026
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