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Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial
OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Menopause
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183764/ https://www.ncbi.nlm.nih.gov/pubmed/37160299 http://dx.doi.org/10.6118/jmm.22026 |
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author | Jenabi, Ensiyeh Khazaei, Salman Aghababaei, Soodabeh Moradkhani, Shirin |
author_facet | Jenabi, Ensiyeh Khazaei, Salman Aghababaei, Soodabeh Moradkhani, Shirin |
author_sort | Jenabi, Ensiyeh |
collection | PubMed |
description | OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel-valerian extract or control. One 500 mg fennel-valerian extract capsule was given twice, daily for 8 weeks. The 500 mg oral placebo capsule (starch) was given the same way. RESULTS: The mean duration of hot flashes increased in both the groups over time (P < 0.001). The mean frequency and severity of hot flashes in the intervention group were significantly lower than in the control group, in the first and second months after intervention (P < 0.050). Women in the fennel-valerian extract group had a significantly lower Pittsburgh Sleep Quality Index score than the control group 2 months after intervention (P = 0.030). CONCLUSIONS: This study found that fennel-valerian extract was effective for relieving sleep disorders as well as the severity and frequency of hot flashes compared with a placebo. |
format | Online Article Text |
id | pubmed-10183764 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | The Korean Society of Menopause |
record_format | MEDLINE/PubMed |
spelling | pubmed-101837642023-05-16 Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial Jenabi, Ensiyeh Khazaei, Salman Aghababaei, Soodabeh Moradkhani, Shirin J Menopausal Med Original Article OBJECTIVES: This study aims to evaluate the effect of a mixture of fennel and valerian extracts on hot flashes and sleep disorders of postmenopausal women in Iran. A randomized trial was conducted. METHODS: A total of 76 postmenopausal women were randomly assigned to either of the two groups: fennel-valerian extract or control. One 500 mg fennel-valerian extract capsule was given twice, daily for 8 weeks. The 500 mg oral placebo capsule (starch) was given the same way. RESULTS: The mean duration of hot flashes increased in both the groups over time (P < 0.001). The mean frequency and severity of hot flashes in the intervention group were significantly lower than in the control group, in the first and second months after intervention (P < 0.050). Women in the fennel-valerian extract group had a significantly lower Pittsburgh Sleep Quality Index score than the control group 2 months after intervention (P = 0.030). CONCLUSIONS: This study found that fennel-valerian extract was effective for relieving sleep disorders as well as the severity and frequency of hot flashes compared with a placebo. The Korean Society of Menopause 2023-04 2023-04-28 /pmc/articles/PMC10183764/ /pubmed/37160299 http://dx.doi.org/10.6118/jmm.22026 Text en Copyright © by The Korean Society of Menopause https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ). |
spellingShingle | Original Article Jenabi, Ensiyeh Khazaei, Salman Aghababaei, Soodabeh Moradkhani, Shirin Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title_full | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title_fullStr | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title_full_unstemmed | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title_short | Effect of Fennel-Valerian Extract on Hot Flashes and Sleep Disorders in Postmenopausal Women: A Randomized Trial |
title_sort | effect of fennel-valerian extract on hot flashes and sleep disorders in postmenopausal women: a randomized trial |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10183764/ https://www.ncbi.nlm.nih.gov/pubmed/37160299 http://dx.doi.org/10.6118/jmm.22026 |
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