Cargando…

Syringic acid demonstrates an anti-inflammatory effect via modulation of the NF-κB-iNOS-COX-2 and JAK-STAT signaling pathways in methyl cellosolve-induced hepato-testicular inflammation in rats

Syringic acid (SACI) is an emerging nutraceutical and antioxidant used in modern Chinese medicine. It has potential neuroprotective, anti-hyperglycemic, and anti-angiogenic properties. Methyl cellosolve (MCEL) has been reported to induce tissue inflammation in the testis, kidney, liver, and lung. Th...

Descripción completa

Detalles Bibliográficos
Autores principales:	Somade, Oluwatobi T., Oyinloye, Babatunji E., Ajiboye, Basiru O., Osukoya, Olukemi A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184048/ https://www.ncbi.nlm.nih.gov/pubmed/37197735 http://dx.doi.org/10.1016/j.bbrep.2023.101484

Ejemplares similares

Effect of syringic acid on steroid and gonadotropic hormones, hematological indices, sperm characteristics and morphologies, and markers of tissue damage in methyl cellosolve-administered rats
por: Somade, Oluwatobi T., et al.
Publicado: (2022)

Effect of Solanum macrocarpon Linn leaf aqueous extract on the brain of an alloxan-induced rat model of diabetes
por: Okesola, Mary A., et al.
Publicado: (2020)

Aqueous extract of Carica papaya Linn. roots potentially attenuates arsenic induced biochemical and genotoxic effects in Wistar rats
por: Ojo, Oluwafemi Adeleke, et al.
Publicado: (2017)

Methyl cellosolve-induced renal oxidative stress and time-dependent up-regulation of pro-inflammatory cytokines, apoptotic, and oncogenic markers in rats
por: Somade, Oluwatobi T., et al.
Publicado: (2020)

The ameliorative activity of Chrysobalanus orbicularis in streptozotocin-induced type II diabetes mellitus rat model
por: Ekakitie, Lisa Ilobekemen, et al.
Publicado: (2021)

Phenyl Cellosolve in the Treatment of Pediculosis
por: Roy, D. N., et al.
Publicado: (1947)

Effect of Flavonoid-Rich Extract From Dalbergiella welwitschii Leaf on Redox, Cholinergic, Monoaminergic, and Purinergic Dysfunction in Oxidative Testicular Injury: Ex Vivo and In Silico Studies
por: Ajiboye, Basiru Olaitan, et al.
Publicado: (2022)

Protective effect of Irvingia gabonensis stem bark extract on cadmium-induced nephrotoxicity in rats
por: Ojo, Oluwafemi Adeleke, et al.
Publicado: (2014)

Cardioprotective and Antioxidant Influence of Aqueous Extracts from Sesamum indicum Seeds on Oxidative Stress Induced by Cadmium in Wistar Rats
por: Oyinloye, Babatunji Emmanuel, et al.
Publicado: (2016)

Ameliorative Activity of Ethanolic Extract of Artocarpus heterophyllus Stem Bark on Alloxan-induced Diabetic Rats
por: Ajiboye, Basiru Olaitan, et al.
Publicado: (2018)

Modulatory Effect of Methanol Extract of Piper guineense in CCl(4)-Induced Hepatotoxicity in Male Rats
por: Oyinloye, Babatunji Emmanuel, et al.
Publicado: (2017)

Ocimum gratissimum Linn. Leaves reduce the key enzymes activities relevant to erectile dysfunction in isolated penile and testicular tissues of rats
por: Ojo, Oluwafemi Adeleke, et al.
Publicado: (2019)

Antihyperglycaemia and related gene expressions of aqueous extract of Gongronema latifolium leaf in alloxan-induced diabetic rats
por: Ajiboye, Basiru O., et al.
Publicado: (2019)

Antioxidative effects of cinnamomi cortex: A potential role of iNOS and COX-II
por: Chung, Jin-Won, et al.
Publicado: (2011)

Supplementation of syringic acid-rich Phrynium pubinerve leaves imparts protection against allergic inflammatory responses by downregulating iNOS, COX-2, and NF-κB expressions
por: Islam, Md Arman, et al.
Publicado: (2023)

Inhibitory Effects of Solvent-Partitioned Fractions of Two Nigerian Herbs (Spondias mombin Linn. and Mangifera indica L.) on α-Amylase and α-Glucosidase
por: Ojo, Oluwafemi Adeleke, et al.
Publicado: (2018)

Investigation of the In Vitro Antioxidant Potential Of Polyphenolic-Rich Extract of Artocarpus heterophyllus Lam Stem Bark and Its Antidiabetic Activity In Streptozotocin-Induced Diabetic Rats
por: Ajiboye, Basiru Olaitan, et al.
Publicado: (2020)

Luteolin, a bioflavonoid inhibits azoxymethane-induced colon carcinogenesis: Involvement of iNOS and COX-2
por: Pandurangan, Ashok Kumar, et al.
Publicado: (2014)

Ventricular hypertrophy blocked delayed anesthetic cardioprotection in rats by alteration of iNOS/COX-2 signaling
por: Ma, Leilei, et al.
Publicado: (2014)

Obesity-Induced Coronary Microvascular Disease Is Prevented by iNOS Deletion and Reversed by iNOS Inhibition
por: Shah, Soham A., et al.
Publicado: (2023)

Pentoxifylline decreases glycemia levels and TNF-alpha, iNOS and COX-2 expressions in diabetic rat pancreas
por: Garcia, Francisca Adilfa O, et al.
Publicado: (2014)

The dual role of iNOS in cancer()
por: Vannini, Federica, et al.
Publicado: (2015)

Immunohistochemical expression of COX2 and iNOS in bladder cancer and its association with urinary schistosomiasis among Sudanese patients
por: Hassan, Hassan Elsiddig, et al.
Publicado: (2013)

High Glucose Induces Endothelial COX2 and iNOS Expression via Inhibition of Monomethyltransferase SETD8 Expression
por: Qi, Jie, et al.
Publicado: (2020)

Profile of Myracrodruon urundeuva Volatile Compounds Ease of Extraction and Biodegradability and In Silico Evaluation of Their Interactions with COX-1 and iNOS
por: Figueiredo, Yuri G., et al.
Publicado: (2022)

Protective Effects of Cirsilineol against Lipopolysaccharide-Induced Inflammation; Insights into HO-1, COX-2, and iNOS Modulation
por: Kim, Go Oun, et al.
Publicado: (2023)

Amphiregulin Induces iNOS and COX-2 Expression through NF-κB and MAPK Signaling in Hepatic Inflammation
por: Heo, Yu Jung, et al.
Publicado: (2023)

Brain function in iNOS knock out or iNOS inhibited (l-NIL) mice under endotoxic shock
por: Schweighöfer, Hanna, et al.
Publicado: (2014)

The expressions of AMACR and iNOS in prostate adenocarcinomas
por: Ozgur, Tumay, et al.
Publicado: (2013)

Targeting iNOS to increase efficacy of immunotherapies
por: Ekmekcioglu, Suhendan, et al.
Publicado: (2017)

Carfilzomib inhibits the proliferation and apoptosis of multiple myeloma cells by inhibiting STAT1/COX-2/iNOS signaling pathway
por: He, Shaolong, et al.
Publicado: (2022)

Syringic acid demonstrates better anti-apoptotic, anti-inflammatory and antioxidative effects than ascorbic acid via maintenance of the endogenous antioxidants and downregulation of pro-inflammatory and apoptotic markers in DMN-induced hepatotoxicity in rats
por: Adeyi, Olubisi E., et al.
Publicado: (2023)

Upregulation of iNOS and phosphorylated eNOS in the implantation‐induced blastocysts of mice
por: Seki, Misato, et al.
Publicado: (2023)

iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection
por: Kumar, Amod, et al.
Publicado: (2017)

Cnidoscolus aconitifolius leaf extract and ascorbate confer amelioration and protection against dimethyl nitrosamine-induced renal toxicity and testicular abnormalities in rats
por: Somade, Oluwatobi T., et al.
Publicado: (2021)

JAK Inhibitors AG-490 and WHI-P154 Decrease IFN-γ-Induced iNOS Expression and NO Production in Macrophages
por: Sareila, Outi, et al.
Publicado: (2006)

Cox-2 Inhibition Protects against Hypoxia/Reoxygenation-Induced Cardiomyocyte Apoptosis via Akt-Dependent Enhancement of iNOS Expression
por: Pang, Lei, et al.
Publicado: (2016)

Aging and Insulin Resistance: Just Say iNOS
por: Evans, Joseph L., et al.
Publicado: (2013)

Ameliorative Activity of Ethanol Extract of Artocarpus heterophyllus Stem Bark on Pancreatic β-Cell Dysfunction in Alloxan-Induced Diabetic Rats
por: Ajiboye, Basiru O., et al.
Publicado: (2016)

Recipient iNOS but Not eNOS Deficiency Reduces Luminal Narrowing in Tracheal Allografts
por: Minamoto, Kanji, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_jmlq3ab0tvtuh5omcvk4crqb9t