Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice

OBJECTIVE: Osteoarthritis (OA), widely seen in the elderly, is featured by cartilage degradation, subchondral bone remolding, and synovium inflammation. Currently, there is no cure for OA development. Phillygenin (PHI), an active ingredient from the Forsythiae Fructus, possesses many biological prop...

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Detalles Bibliográficos
Autores principales: Zhang, Peng, Jin, Yesheng, Xia, Wei, Wang, Xiaotong, Zhou, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184049/
https://www.ncbi.nlm.nih.gov/pubmed/37197096
http://dx.doi.org/10.1016/j.jot.2023.03.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184049/
https://www.ncbi.nlm.nih.gov/pubmed/37197096
http://dx.doi.org/10.1016/j.jot.2023.03.002

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