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Development of a Potent Nurr1 Agonist Tool for In Vivo Applications

[Image: see text] Nuclear receptor related 1 (Nurr1) is a neuroprotective transcription factor and an emerging target in neurodegenerative diseases. Despite strong evidence for a role in Parkinson’s and Alzheimer’s disease, pharmacological control and validation of Nurr1 are hindered by a lack of su...

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Detalles Bibliográficos
Autores principales: Vietor, Jan, Gege, Christian, Stiller, Tanja, Busch, Romy, Schallmayer, Espen, Kohlhof, Hella, Höfner, Georg, Pabel, Jörg, Marschner, Julian A., Merk, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184128/
https://www.ncbi.nlm.nih.gov/pubmed/37127285
http://dx.doi.org/10.1021/acs.jmedchem.3c00415

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