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Size matters in telomere biology disorders ‒ expanding phenotypic spectrum in patients with long or short telomeres
The end of each chromosome consists of a DNA region termed the telomeres. The telomeres serve as a protective shield against degradation of the coding DNA sequence, as the DNA strand inevitably ‒ with each cell division ‒ is shortened. Inherited genetic variants cause telomere biology disorders when...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184327/ https://www.ncbi.nlm.nih.gov/pubmed/37189188 http://dx.doi.org/10.1186/s13053-023-00251-7 |