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Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans

BACKGROUND: The variation in the rate at which humans age may be rooted in early events acting through the genomic regions that are influenced by such events and subsequently are related to health phenotypes in later life. The parent-of-origin-effect (POE)-regulated methylome includes regions enrich...

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Detalles Bibliográficos
Autores principales: Gao, Chenhao, Amador, Carmen, Walker, Rosie M., Campbell, Archie, Madden, Rebecca A., Adams, Mark J., Bai, Xiaomeng, Liu, Ying, Li, Miaoxin, Hayward, Caroline, Porteous, David J., Shen, Xueyi, Evans, Kathryn L., Haley, Chris S., McIntosh, Andrew M., Navarro, Pau, Zeng, Yanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184337/
https://www.ncbi.nlm.nih.gov/pubmed/37189164
http://dx.doi.org/10.1186/s13059-023-02953-6