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Phenome-wide analyses identify an association between the parent-of-origin effects dependent methylome and the rate of aging in humans
BACKGROUND: The variation in the rate at which humans age may be rooted in early events acting through the genomic regions that are influenced by such events and subsequently are related to health phenotypes in later life. The parent-of-origin-effect (POE)-regulated methylome includes regions enrich...
Autores principales: | Gao, Chenhao, Amador, Carmen, Walker, Rosie M., Campbell, Archie, Madden, Rebecca A., Adams, Mark J., Bai, Xiaomeng, Liu, Ying, Li, Miaoxin, Hayward, Caroline, Porteous, David J., Shen, Xueyi, Evans, Kathryn L., Haley, Chris S., McIntosh, Andrew M., Navarro, Pau, Zeng, Yanni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184337/ https://www.ncbi.nlm.nih.gov/pubmed/37189164 http://dx.doi.org/10.1186/s13059-023-02953-6 |
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