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Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study

OBJECTIVES: To assess the prevalence of dry eye disease (DED) in the Uyghur population in Hotan, Xinjiang, and to identify risk factors associated with this disorder. METHODS: Between January and September of 2020, 5,121 Uyghur subjects aged 18 − 98 years from 105 villages were selected and studied...

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Autores principales: Li, Xiaolong, Wang, Zhen, Mu, Jingyu, Puerkaiti, Hamila, Nulahou, Ayinu, Zhang, Jie, Zhao, Yong, Sun, Qi, Li, Yuanyuan, Wang, Yan, Gao, Yunxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184355/
https://www.ncbi.nlm.nih.gov/pubmed/37189099
http://dx.doi.org/10.1186/s12886-023-02955-9
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author Li, Xiaolong
Wang, Zhen
Mu, Jingyu
Puerkaiti, Hamila
Nulahou, Ayinu
Zhang, Jie
Zhao, Yong
Sun, Qi
Li, Yuanyuan
Wang, Yan
Gao, Yunxian
author_facet Li, Xiaolong
Wang, Zhen
Mu, Jingyu
Puerkaiti, Hamila
Nulahou, Ayinu
Zhang, Jie
Zhao, Yong
Sun, Qi
Li, Yuanyuan
Wang, Yan
Gao, Yunxian
author_sort Li, Xiaolong
collection PubMed
description OBJECTIVES: To assess the prevalence of dry eye disease (DED) in the Uyghur population in Hotan, Xinjiang, and to identify risk factors associated with this disorder. METHODS: Between January and September of 2020, 5,121 Uyghur subjects aged 18 − 98 years from 105 villages were selected and studied cross-sectionally using a whole-group random sampling method in the Hotan area, Xinjiang, China. The Ocular Surface Disease Index questionnaire was used to collect subjective symptoms of DED and examine tear-film break-up times. The break up time and Schirmer’s test were used to collect objective signs, to determine the prevalence of DED and its risk factors. RESULTS: A total of 5,121 subjects aged 18 − 98 years were recruited from the Uyghur population in the Hotan region of Xinjiang, China, for eye examinations and questionnaire surveys. A total of 40.6% (2,078/5,121) were diagnosed with DED, of which 38.3% were male and 41.9% were female. The prevalence of DED was the highest in subjects ≥ 65 years of age, with 47.8% in males and 53.3% in females. The lowest occurrence was in subjects 18 − 44 years of age, with 32.5% in males and 33.7% in females. Older age, tea drinking, and staying awake late were risk factors affecting the severity of DED prevalence (p < 0.05), but there was no significant difference in sex, presence of diabetes, or presence of hypertension (p > 0.05). CONCLUSION: The prevalence of DED in the study population was 40.6%, and its prevalence was higher in females, when compared with males. The prevalence of dry eye also increased with age, and at an advanced age, female sex, smoking, staying awake late, and not exercising were risk factors for DED.
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spelling pubmed-101843552023-05-16 Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study Li, Xiaolong Wang, Zhen Mu, Jingyu Puerkaiti, Hamila Nulahou, Ayinu Zhang, Jie Zhao, Yong Sun, Qi Li, Yuanyuan Wang, Yan Gao, Yunxian BMC Ophthalmol Research OBJECTIVES: To assess the prevalence of dry eye disease (DED) in the Uyghur population in Hotan, Xinjiang, and to identify risk factors associated with this disorder. METHODS: Between January and September of 2020, 5,121 Uyghur subjects aged 18 − 98 years from 105 villages were selected and studied cross-sectionally using a whole-group random sampling method in the Hotan area, Xinjiang, China. The Ocular Surface Disease Index questionnaire was used to collect subjective symptoms of DED and examine tear-film break-up times. The break up time and Schirmer’s test were used to collect objective signs, to determine the prevalence of DED and its risk factors. RESULTS: A total of 5,121 subjects aged 18 − 98 years were recruited from the Uyghur population in the Hotan region of Xinjiang, China, for eye examinations and questionnaire surveys. A total of 40.6% (2,078/5,121) were diagnosed with DED, of which 38.3% were male and 41.9% were female. The prevalence of DED was the highest in subjects ≥ 65 years of age, with 47.8% in males and 53.3% in females. The lowest occurrence was in subjects 18 − 44 years of age, with 32.5% in males and 33.7% in females. Older age, tea drinking, and staying awake late were risk factors affecting the severity of DED prevalence (p < 0.05), but there was no significant difference in sex, presence of diabetes, or presence of hypertension (p > 0.05). CONCLUSION: The prevalence of DED in the study population was 40.6%, and its prevalence was higher in females, when compared with males. The prevalence of dry eye also increased with age, and at an advanced age, female sex, smoking, staying awake late, and not exercising were risk factors for DED. BioMed Central 2023-05-15 /pmc/articles/PMC10184355/ /pubmed/37189099 http://dx.doi.org/10.1186/s12886-023-02955-9 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Li, Xiaolong
Wang, Zhen
Mu, Jingyu
Puerkaiti, Hamila
Nulahou, Ayinu
Zhang, Jie
Zhao, Yong
Sun, Qi
Li, Yuanyuan
Wang, Yan
Gao, Yunxian
Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title_full Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title_fullStr Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title_full_unstemmed Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title_short Prevalence and associated risk factors of dry eye disease in Hotan, Xinjiang: a cross-sectional study
title_sort prevalence and associated risk factors of dry eye disease in hotan, xinjiang: a cross-sectional study
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184355/
https://www.ncbi.nlm.nih.gov/pubmed/37189099
http://dx.doi.org/10.1186/s12886-023-02955-9
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