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Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
Adult hematopoietic stem and progenitor cells (HSPCs) respond directly to inflammation and infection, causing both acute and persistent changes to quiescence, mobilization, and differentiation. Here we show that murine fetal HSPCs respond to prenatal inflammation in utero and that the fetal response...
Autores principales: | López, Diego A., Apostol, April C., Lebish, Eric J., Valencia, Clint H., Romero-Mulero, Mari Carmen, Pavlovich, Polina V., Hernandez, Gloria E., Forsberg, E. Camilla, Cabezas-Wallscheid, Nina, Beaudin, Anna E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184520/ https://www.ncbi.nlm.nih.gov/pubmed/36417858 http://dx.doi.org/10.1016/j.celrep.2022.111677 |
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