Specific Detection of Proteins by a Nanobody-Functionalized Nanopore Sensor

[Image: see text] Nanopores are label-free single-molecule analytical tools that show great potential for stochastic sensing of proteins. Here, we described a ClyA nanopore functionalized with different nanobodies through a 5–6 nm DNA linker at its periphery. Ty1, 2Rs15d, 2Rb17c, and nb22 nanobodies...

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Detalles Bibliográficos
Autores principales: Zhang, Xialin, Galenkamp, Nicole Stéphanie, van der Heide, Nieck Jordy, Moreno, Julián, Maglia, Giovanni, Kjems, Jørgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184537/
https://www.ncbi.nlm.nih.gov/pubmed/37127291
http://dx.doi.org/10.1021/acsnano.2c12733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184537/
https://www.ncbi.nlm.nih.gov/pubmed/37127291
http://dx.doi.org/10.1021/acsnano.2c12733

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