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Structural basis for breadth development in the HIV-1 V3-glycan targeting DH270 antibody clonal lineage

Antibody affinity maturation enables adaptive immune responses to a wide range of pathogens. In some individuals broadly neutralizing antibodies develop to recognize rapidly mutating pathogens with extensive sequence diversity. Vaccine design for pathogens such as HIV-1 and influenza has therefore f...

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Detalles Bibliográficos
Autores principales:	Henderson, Rory, Zhou, Ye, Stalls, Victoria, Wiehe, Kevin, Saunders, Kevin O., Wagh, Kshitij, Anasti, Kara, Barr, Maggie, Parks, Robert, Alam, S. Munir, Korber, Bette, Haynes, Barton F., Bartesaghi, Alberto, Acharya, Priyamvada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184639/ https://www.ncbi.nlm.nih.gov/pubmed/37188681 http://dx.doi.org/10.1038/s41467-023-38108-1

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