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A wild rice-derived peptide R14 ameliorates monosodium urate crystals-induced IL-1β secretion through inhibition of NF-κB signaling and NLRP3 inflammasome activation

Gout is an inflammatory arthritis initiated by the deposition of monosodium urate crystals (MSU) around the joints and surrounding tissues. MSU crystals activate the nucleotide-binding oligomerization domain-like receptor containing pyrin domain 3 (NLRP3) inflammasome to the release of interleukin-1...

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Detalles Bibliográficos
Autores principales: Charoenwutthikun, Supattra, Chanjitwiriya, Kasem, Roytrakul, Sittiruk, Kunthalert, Duangkamol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184658/
https://www.ncbi.nlm.nih.gov/pubmed/37197585
http://dx.doi.org/10.7717/peerj.15295

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