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Cytosolic Enzymes Generate Cannabinoid Metabolites 7-Carboxycannabidiol and 11-Nor-9-carboxytetrahydrocannabinol

[Image: see text] The cannabinoids cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC) undergo extensive oxidative metabolism in the liver. Although cytochromes P450 form the primary, pharmacologically active, hydroxylated metabolites of CBD and THC, less is known about the enzymes that generat...

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Detalles Bibliográficos
Autores principales: Beers, Jessica L., Authement, Aurora K., Isoherranen, Nina, Jackson, Klarissa D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184666/
https://www.ncbi.nlm.nih.gov/pubmed/37197460
http://dx.doi.org/10.1021/acsmedchemlett.3c00017