Paracingulin recruits CAMSAP3 to tight junctions and regulates microtubule and polarized epithelial cell organization

Paracingulin (CGNL1) is recruited to tight junctions (TJs) by ZO-1 and to adherens junctions (AJs) by PLEKHA7. PLEKHA7 has been reported to bind to the microtubule minus-end-binding protein CAMSAP3, to tether microtubules to the AJs. Here, we show that knockout (KO) of CGNL1, but not of PLEKHA7, res...

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Detalles Bibliográficos
Autores principales: Flinois, Arielle, Méan, Isabelle, Mutero-Maeda, Annick, Guillemot, Laurent, Citi, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184829/
https://www.ncbi.nlm.nih.gov/pubmed/37013686
http://dx.doi.org/10.1242/jcs.260745

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10184829/
https://www.ncbi.nlm.nih.gov/pubmed/37013686
http://dx.doi.org/10.1242/jcs.260745

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