Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft

Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is among the spectrum of monoclonal protein-associated renal diseases, with only about 15 case reports in children. We report a 7-year-old boy with biopsy-proven crescentic PGNMID who progressed to end-stage renal dise...

Descripción completa

Detalles Bibliográficos
Autores principales: Madireddy, Nishika, Patil, Radhika, Priyadarshini, Shweta, Varma, Manish C., Garre, Satyakishore, Gowrishankar, Swarnalata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2023
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185008/
https://www.ncbi.nlm.nih.gov/pubmed/37197047
http://dx.doi.org/10.4103/ijn.ijn_380_21
_version_ 1785042257887363072
author Madireddy, Nishika
Patil, Radhika
Priyadarshini, Shweta
Varma, Manish C.
Garre, Satyakishore
Gowrishankar, Swarnalata
author_facet Madireddy, Nishika
Patil, Radhika
Priyadarshini, Shweta
Varma, Manish C.
Garre, Satyakishore
Gowrishankar, Swarnalata
author_sort Madireddy, Nishika
collection PubMed
description Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is among the spectrum of monoclonal protein-associated renal diseases, with only about 15 case reports in children. We report a 7-year-old boy with biopsy-proven crescentic PGNMID who progressed to end-stage renal disease within a few months of presentation. He then received a renal transplant with his grandmother as a donor. Proteinuria was detected at 27 months post-transplant and an allograft biopsy revealed a recurrent disease.
format Online
Article
Text
id pubmed-10185008
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-101850082023-05-16 Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft Madireddy, Nishika Patil, Radhika Priyadarshini, Shweta Varma, Manish C. Garre, Satyakishore Gowrishankar, Swarnalata Indian J Nephrol Case Report Proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID) is among the spectrum of monoclonal protein-associated renal diseases, with only about 15 case reports in children. We report a 7-year-old boy with biopsy-proven crescentic PGNMID who progressed to end-stage renal disease within a few months of presentation. He then received a renal transplant with his grandmother as a donor. Proteinuria was detected at 27 months post-transplant and an allograft biopsy revealed a recurrent disease. Wolters Kluwer - Medknow 2023 2022-10-02 /pmc/articles/PMC10185008/ /pubmed/37197047 http://dx.doi.org/10.4103/ijn.ijn_380_21 Text en Copyright: © 2022 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Madireddy, Nishika
Patil, Radhika
Priyadarshini, Shweta
Varma, Manish C.
Garre, Satyakishore
Gowrishankar, Swarnalata
Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title_full Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title_fullStr Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title_full_unstemmed Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title_short Proliferative Glomerulonephritis with Monoclonal Immunoglobulins in a Child with Recurrence in the Allograft
title_sort proliferative glomerulonephritis with monoclonal immunoglobulins in a child with recurrence in the allograft
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185008/
https://www.ncbi.nlm.nih.gov/pubmed/37197047
http://dx.doi.org/10.4103/ijn.ijn_380_21
work_keys_str_mv AT madireddynishika proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft
AT patilradhika proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft
AT priyadarshinishweta proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft
AT varmamanishc proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft
AT garresatyakishore proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft
AT gowrishankarswarnalata proliferativeglomerulonephritiswithmonoclonalimmunoglobulinsinachildwithrecurrenceintheallograft

Ejemplares similares