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Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six mon...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185332/ https://www.ncbi.nlm.nih.gov/pubmed/37197118 http://dx.doi.org/10.7759/cureus.37623 |
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author | Osuoji, Olive C Uebelhoer, Nathan S Erickson, Christof P Calame, Antoanella Cohen, Philip R |
author_facet | Osuoji, Olive C Uebelhoer, Nathan S Erickson, Christof P Calame, Antoanella Cohen, Philip R |
author_sort | Osuoji, Olive C |
collection | PubMed |
description | Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six months duration. The nodule could be easily moved from one location to another. An incisional biopsy was performed. Microscopic examination of the tissue specimen showed islands of basophilic calcium material in dense sclerotic dermal connective tissue establishing the diagnosis of calcinosis cutis. Mobile solitary calcification is an unusual presentation of idiopathic calcinosis cutis. In addition to idiopathic calcinosis cutis, benign mobile subcutaneous tumors have also been derived from adnexal structures of hair follicles and adipose tissue. Hence, not only idiopathic calcinosis cutis, but also subepidermal calcinosis in the ocular adnexa, proliferating trichilemmal cyst with focal calcification, and mobile encapsulated adipose tissue can present as a mobile subcutaneous nodule. The features of idiopathic calcinosis presenting as a mobile subcutaneous nodule as well as the characteristics of other benign mobile subcutaneous tumors are reviewed. |
format | Online Article Text |
id | pubmed-10185332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-101853322023-05-16 Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors Osuoji, Olive C Uebelhoer, Nathan S Erickson, Christof P Calame, Antoanella Cohen, Philip R Cureus Dermatology Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six months duration. The nodule could be easily moved from one location to another. An incisional biopsy was performed. Microscopic examination of the tissue specimen showed islands of basophilic calcium material in dense sclerotic dermal connective tissue establishing the diagnosis of calcinosis cutis. Mobile solitary calcification is an unusual presentation of idiopathic calcinosis cutis. In addition to idiopathic calcinosis cutis, benign mobile subcutaneous tumors have also been derived from adnexal structures of hair follicles and adipose tissue. Hence, not only idiopathic calcinosis cutis, but also subepidermal calcinosis in the ocular adnexa, proliferating trichilemmal cyst with focal calcification, and mobile encapsulated adipose tissue can present as a mobile subcutaneous nodule. The features of idiopathic calcinosis presenting as a mobile subcutaneous nodule as well as the characteristics of other benign mobile subcutaneous tumors are reviewed. Cureus 2023-04-15 /pmc/articles/PMC10185332/ /pubmed/37197118 http://dx.doi.org/10.7759/cureus.37623 Text en Copyright © 2023, Osuoji et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Dermatology Osuoji, Olive C Uebelhoer, Nathan S Erickson, Christof P Calame, Antoanella Cohen, Philip R Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title | Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title_full | Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title_fullStr | Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title_full_unstemmed | Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title_short | Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors |
title_sort | mobile subcutaneous calcinosis cutis: a case report of a mobile solitary subepidermal calcified nodule on a woman’s leg and a review of mobile subcutaneous tumors |
topic | Dermatology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185332/ https://www.ncbi.nlm.nih.gov/pubmed/37197118 http://dx.doi.org/10.7759/cureus.37623 |
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