Cargando…

Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors

Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six mon...

Descripción completa

Detalles Bibliográficos
Autores principales: Osuoji, Olive C, Uebelhoer, Nathan S, Erickson, Christof P, Calame, Antoanella, Cohen, Philip R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185332/
https://www.ncbi.nlm.nih.gov/pubmed/37197118
http://dx.doi.org/10.7759/cureus.37623
_version_ 1785042333296754688
author Osuoji, Olive C
Uebelhoer, Nathan S
Erickson, Christof P
Calame, Antoanella
Cohen, Philip R
author_facet Osuoji, Olive C
Uebelhoer, Nathan S
Erickson, Christof P
Calame, Antoanella
Cohen, Philip R
author_sort Osuoji, Olive C
collection PubMed
description Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six months duration. The nodule could be easily moved from one location to another. An incisional biopsy was performed. Microscopic examination of the tissue specimen showed islands of basophilic calcium material in dense sclerotic dermal connective tissue establishing the diagnosis of calcinosis cutis. Mobile solitary calcification is an unusual presentation of idiopathic calcinosis cutis. In addition to idiopathic calcinosis cutis, benign mobile subcutaneous tumors have also been derived from adnexal structures of hair follicles and adipose tissue. Hence, not only idiopathic calcinosis cutis, but also subepidermal calcinosis in the ocular adnexa, proliferating trichilemmal cyst with focal calcification, and mobile encapsulated adipose tissue can present as a mobile subcutaneous nodule. The features of idiopathic calcinosis presenting as a mobile subcutaneous nodule as well as the characteristics of other benign mobile subcutaneous tumors are reviewed.
format Online
Article
Text
id pubmed-10185332
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-101853322023-05-16 Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors Osuoji, Olive C Uebelhoer, Nathan S Erickson, Christof P Calame, Antoanella Cohen, Philip R Cureus Dermatology Calcinosis cutis describes the deposition of calcium in the dermis. A case of a 69-year-old woman with idiopathic calcinosis cutis that presented as a mobile subcutaneous nodule is described. The patient had an asymptomatic, firm, mobile subcutaneous nodule on her right lower leg of at least six months duration. The nodule could be easily moved from one location to another. An incisional biopsy was performed. Microscopic examination of the tissue specimen showed islands of basophilic calcium material in dense sclerotic dermal connective tissue establishing the diagnosis of calcinosis cutis. Mobile solitary calcification is an unusual presentation of idiopathic calcinosis cutis. In addition to idiopathic calcinosis cutis, benign mobile subcutaneous tumors have also been derived from adnexal structures of hair follicles and adipose tissue. Hence, not only idiopathic calcinosis cutis, but also subepidermal calcinosis in the ocular adnexa, proliferating trichilemmal cyst with focal calcification, and mobile encapsulated adipose tissue can present as a mobile subcutaneous nodule. The features of idiopathic calcinosis presenting as a mobile subcutaneous nodule as well as the characteristics of other benign mobile subcutaneous tumors are reviewed. Cureus 2023-04-15 /pmc/articles/PMC10185332/ /pubmed/37197118 http://dx.doi.org/10.7759/cureus.37623 Text en Copyright © 2023, Osuoji et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Dermatology
Osuoji, Olive C
Uebelhoer, Nathan S
Erickson, Christof P
Calame, Antoanella
Cohen, Philip R
Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title_full Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title_fullStr Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title_full_unstemmed Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title_short Mobile Subcutaneous Calcinosis Cutis: A Case Report of a Mobile Solitary Subepidermal Calcified Nodule on a Woman’s Leg and a Review of Mobile Subcutaneous Tumors
title_sort mobile subcutaneous calcinosis cutis: a case report of a mobile solitary subepidermal calcified nodule on a woman’s leg and a review of mobile subcutaneous tumors
topic Dermatology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185332/
https://www.ncbi.nlm.nih.gov/pubmed/37197118
http://dx.doi.org/10.7759/cureus.37623
work_keys_str_mv AT osuojiolivec mobilesubcutaneouscalcinosiscutisacasereportofamobilesolitarysubepidermalcalcifiednoduleonawomanslegandareviewofmobilesubcutaneoustumors
AT uebelhoernathans mobilesubcutaneouscalcinosiscutisacasereportofamobilesolitarysubepidermalcalcifiednoduleonawomanslegandareviewofmobilesubcutaneoustumors
AT ericksonchristofp mobilesubcutaneouscalcinosiscutisacasereportofamobilesolitarysubepidermalcalcifiednoduleonawomanslegandareviewofmobilesubcutaneoustumors
AT calameantoanella mobilesubcutaneouscalcinosiscutisacasereportofamobilesolitarysubepidermalcalcifiednoduleonawomanslegandareviewofmobilesubcutaneoustumors
AT cohenphilipr mobilesubcutaneouscalcinosiscutisacasereportofamobilesolitarysubepidermalcalcifiednoduleonawomanslegandareviewofmobilesubcutaneoustumors