SEL1L–HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool

Stimulator of interferon genes (STING) orchestrates the production of proinflammatory cytokines in response to cytosolic double-stranded DNA; however, the pathophysiological significance and molecular mechanism underlying the folding and maturation of nascent STING protein at the endoplasmic reticul...

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Detalles Bibliográficos
Autores principales: Ji, Yewei, Luo, Yuan, Wu, Yating, Sun, Yao, Zhao, Lianfeng, Xue, Zhen, Sun, Mengqi, Wei, Xiaoqiong, He, Zinan, Wu, Shuangcheng Alivia, Lin, Liangguang Leo, Lu, You, Chang, Lei, Chen, Fei, Chen, Siyu, Qian, Wei, Xu, Xiaoxi, Chen, Shengnuo, Pan, Dongli, Zhou, Zhangsen, Xia, Sheng, Hu, Chih-Chi Andrew, Liang, Tingbo, Qi, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185471/
https://www.ncbi.nlm.nih.gov/pubmed/37142791
http://dx.doi.org/10.1038/s41556-023-01138-4

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