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Molecular mechanism of anionic stabilizer for telomere G-quadruplex

Telomere DNA assumes a high-order G-quadruplex (G4) structure, stabilization of which prevents telomere lengthening by telomerase in cancer. Through applying combined molecular simulation methods, an investigation on the selective binding mechanism of anionic phthalocyanine 3,4ʹ,4ʹʹ,4ʹʹʹ-tetrasulfon...

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Detalles Bibliográficos
Autores principales:	Wang, Zhiguo, Li, Jianfeng, Liu, Jun, Wang, Lihui, Lu, Yanhua, Liu, Jun-Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Biophysics Reports Editorial Office 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185486/ https://www.ncbi.nlm.nih.gov/pubmed/37288004 http://dx.doi.org/10.52601/bpr.2022.220039

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