Predictive network analysis identifies JMJD6 and other potential key drivers in Alzheimer’s disease

Despite decades of genetic studies on late-onset Alzheimer’s disease, the underlying molecular mechanisms remain unclear. To better comprehend its complex etiology, we use an integrative approach to build robust predictive (causal) network models using two large human multi-omics datasets. We deline...

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Detalles Bibliográficos
Autores principales: Merchant, Julie P., Zhu, Kuixi, Henrion, Marc Y. R., Zaidi, Syed S. A., Lau, Branden, Moein, Sara, Alamprese, Melissa L., Pearse, Richard V., Bennett, David A., Ertekin-Taner, Nilüfer, Young-Pearse, Tracy L., Chang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185548/
https://www.ncbi.nlm.nih.gov/pubmed/37188718
http://dx.doi.org/10.1038/s42003-023-04791-5

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