Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis

Recent studies have shown that the tumor extracellular matrix (ECM) associates with immunosuppression, and that targeting the ECM can improve immune infiltration and responsiveness to immunotherapy. A question that remains unresolved is whether the ECM directly educates the immune phenotypes seen in...

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Detalles Bibliográficos
Autores principales: Puttock, E. H., Tyler, E. J., Manni, M., Maniati, E., Butterworth, C., Burger Ramos, M., Peerani, E., Hirani, P., Gauthier, V., Liu, Y., Maniscalco, G., Rajeeve, V., Cutillas, P., Trevisan, C., Pozzobon, M., Lockley, M., Rastrick, J., Läubli, H., White, A., Pearce, O. M. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185550/
https://www.ncbi.nlm.nih.gov/pubmed/37188691
http://dx.doi.org/10.1038/s41467-023-38093-5

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