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An effective validation of analytical method for determination of a polar complexing agent: the illustrative case of cytotoxic bleomycin
The effectiveness of highly polar agents in cancer treatment is well recognized, but their physicochemical properties make their analytical determination a demanding task. Their analysis requires peculiar sample preparation and chromatographic separation, which heavily impacts the precision of such ...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185589/ https://www.ncbi.nlm.nih.gov/pubmed/37041279 http://dx.doi.org/10.1007/s00216-023-04675-x |