Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes

BACKGROUND: Infertility, which is defined as the inability to conceive after at least 12 months of regular unprotected sexual intercourses, affects about 15–20% of couples worldwide and a male factor is involved in about half of the cases. The development of assisted reproductive technology (ART) ma...

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Autores principales: Mazzilli, R., Rucci, C., Vaiarelli, A., Cimadomo, D., Ubaldi, F. M., Foresta, C., Ferlin, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185595/
https://www.ncbi.nlm.nih.gov/pubmed/36633791
http://dx.doi.org/10.1007/s40618-022-02000-4
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author Mazzilli, R.
Rucci, C.
Vaiarelli, A.
Cimadomo, D.
Ubaldi, F. M.
Foresta, C.
Ferlin, A.
author_facet Mazzilli, R.
Rucci, C.
Vaiarelli, A.
Cimadomo, D.
Ubaldi, F. M.
Foresta, C.
Ferlin, A.
author_sort Mazzilli, R.
collection PubMed
description BACKGROUND: Infertility, which is defined as the inability to conceive after at least 12 months of regular unprotected sexual intercourses, affects about 15–20% of couples worldwide and a male factor is involved in about half of the cases. The development of assisted reproductive technology (ART) made it possible to conceive also to individuals affected from severe oligospermia or azoospermia. However, the impact of the male factor on embryo development, implantation, prevalence of chromosomal abnormalities, genetic and epigenetic alterations, and clinical and obstetric outcomes is still controversial. PURPOSE: This narrative review examines the indications, minimum access criteria, and outcomes by individual ART technique in relation to the male factor.
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spelling pubmed-101855952023-05-17 Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes Mazzilli, R. Rucci, C. Vaiarelli, A. Cimadomo, D. Ubaldi, F. M. Foresta, C. Ferlin, A. J Endocrinol Invest Review BACKGROUND: Infertility, which is defined as the inability to conceive after at least 12 months of regular unprotected sexual intercourses, affects about 15–20% of couples worldwide and a male factor is involved in about half of the cases. The development of assisted reproductive technology (ART) made it possible to conceive also to individuals affected from severe oligospermia or azoospermia. However, the impact of the male factor on embryo development, implantation, prevalence of chromosomal abnormalities, genetic and epigenetic alterations, and clinical and obstetric outcomes is still controversial. PURPOSE: This narrative review examines the indications, minimum access criteria, and outcomes by individual ART technique in relation to the male factor. Springer International Publishing 2023-01-12 2023 /pmc/articles/PMC10185595/ /pubmed/36633791 http://dx.doi.org/10.1007/s40618-022-02000-4 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review
Mazzilli, R.
Rucci, C.
Vaiarelli, A.
Cimadomo, D.
Ubaldi, F. M.
Foresta, C.
Ferlin, A.
Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title_full Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title_fullStr Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title_full_unstemmed Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title_short Male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
title_sort male factor infertility and assisted reproductive technologies: indications, minimum access criteria and outcomes
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185595/
https://www.ncbi.nlm.nih.gov/pubmed/36633791
http://dx.doi.org/10.1007/s40618-022-02000-4
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