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iPSC-Derived Pancreatic Progenitors Lacking FOXA2 Reveal Alterations in miRNA Expression Targeting Key Pancreatic Genes

Recently, we reported that forkhead box A2 (FOXA2) is required for the development of human pancreatic α- and β-cells. However, whether miRNAs play a role in regulating pancreatic genes during pancreatic development in the absence of FOXA2 expression is largely unknown. Here, we aimed to capture the...

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Detalles Bibliográficos
Autores principales: Aldous, Noura, Elsayed, Ahmed K., Alajez, Nehad M., Abdelalim, Essam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185633/
https://www.ncbi.nlm.nih.gov/pubmed/36749553
http://dx.doi.org/10.1007/s12015-023-10515-3