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In utero delivery of miRNA induces epigenetic alterations and corrects pulmonary pathology in congenital diaphragmatic hernia
Structural fetal diseases, such as congenital diaphragmatic hernia (CDH) can be diagnosed prenatally. Neonates with CDH are healthy in utero as gas exchange is managed by the placenta, but impaired lung function results in critical illness from the time a baby takes its first breath. MicroRNA (miR)...
Autores principales: | Ullrich, Sarah J., Yung, Nicholas K., Bauer-Pisani, Tory J., Maassel, Nathan L., Guerra, Mary Elizabeth, Freedman-Weiss, Mollie, Ahle, Samantha L., Ricciardi, Adele S., Sauler, Maor, Saltzman, W. Mark, Piotrowski-Daspit, Alexandra S., Stitelman, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185702/ https://www.ncbi.nlm.nih.gov/pubmed/37200861 http://dx.doi.org/10.1016/j.omtn.2023.04.018 |
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