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Case report: Hepatotoxicity and nephrotoxicity induced by methotrexate in a paediatric patient, what is the role of precision medicine in 2023?

Methotrexate is an immunosuppressant and chemotherapeutic agent used in the treatment of a range of autoimmune disorders and cancers. Its main serious adverse effects, bone marrow suppression and gastrointestinal complications, arise from its antimetabolite effect. Nevertheless, hepatotoxicity and n...

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Detalles Bibliográficos
Autores principales:	El Masri, Ali El Rida, Tobler, Caroline, Willemijn, Breunis, Von Bueren, Andre O., Ansari, Marc, Samer, Caroline Flora
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185764/ https://www.ncbi.nlm.nih.gov/pubmed/37201023 http://dx.doi.org/10.3389/fphar.2023.1130548

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