Neuroimaging findings in preclinical amyotrophic lateral sclerosis models—How well do they mimic the clinical phenotype? A systematic review

BACKGROUND AND OBJECTIVES: Animal models for motor neuron diseases (MND) such as amyotrophic lateral sclerosis (ALS) are commonly used in preclinical research. However, it is insufficiently understood how much findings from these model systems can be translated to humans. Thus, we aimed at systemati...

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Detalles Bibliográficos
Autores principales: Cannon, Amelia Elaine, Zürrer, Wolfgang Emanuel, Zejlon, Charlotte, Kulcsar, Zsolt, Lewandowski, Sebastian, Piehl, Fredrik, Granberg, Tobias, Ineichen, Benjamin Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185801/
https://www.ncbi.nlm.nih.gov/pubmed/37205225
http://dx.doi.org/10.3389/fvets.2023.1135282

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