Functional characterization of C21ORF2 association with the NEK1 kinase mutated in human in diseases

The NEK1 kinase controls ciliogenesis, mitosis, and DNA repair, and NEK1 mutations cause human diseases including axial spondylometaphyseal dysplasia and amyotrophic lateral sclerosis. C21ORF2 mutations cause a similar pattern of human diseases, suggesting close functional links with NEK1. Here, we...

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Detalles Bibliográficos
Autores principales: Gregorczyk, Mateusz, Pastore, Graziana, Muñoz, Ivan, Carroll, Thomas, Streubel, Johanna, Munro, Meagan, Lis, Pawel, Lange, Sven, Lamoliatte, Frederic, Macartney, Thomas, Toth, Rachel, Brown, Fiona, Hastie, James, Pereira, Gislene, Durocher, Daniel, Rouse, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185812/
https://www.ncbi.nlm.nih.gov/pubmed/37188479
http://dx.doi.org/10.26508/lsa.202201740

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