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Repurposing pentamidine for cancer immunotherapy by targeting the PD1/PD-L1 immune checkpoint

Immunotherapy has emerged as an effective therapeutic approach to several cancer types. The reinvigoration of tumor-infiltrating lymphocyte-mediated immune responses via the blockade of immune checkpoint markers, such as program cell death-1 (PD-1) or its cognate ligand PD-L1, has been the basis for...

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Detalles Bibliográficos
Autores principales: Gu, Tingxuan, Tian, Xueli, Wang, Yuanyuan, Yang, Wenqian, Li, Wenwen, Song, Mengqiu, Zhao, Ran, Wang, Mengqiao, Gao, Quanli, Li, Tiepeng, Zhang, Chengjuan, Kundu, Joydeb Kumar, Liu, Kangdong, Dong, Zigang, Lee, Mee-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185823/
https://www.ncbi.nlm.nih.gov/pubmed/37205112
http://dx.doi.org/10.3389/fimmu.2023.1145028

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