Lipid metabolism in tumor immunology and immunotherapy

Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their...

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Detalles Bibliográficos
Autores principales: Duong, Lisa K., Corbali, Halil Ibrahim, Riad, Thomas S., Ganjoo, Shonik, Nanez, Selene, Voss, Tiffany, Barsomium, Hampartsum, Welsh, James, Cortez, Maria Angelica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185832/
https://www.ncbi.nlm.nih.gov/pubmed/37205182
http://dx.doi.org/10.3389/fonc.2023.1187279
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author Duong, Lisa K.
Corbali, Halil Ibrahim
Riad, Thomas S.
Ganjoo, Shonik
Nanez, Selene
Voss, Tiffany
Barsomium, Hampartsum
Welsh, James
Cortez, Maria Angelica
author_facet Duong, Lisa K.
Corbali, Halil Ibrahim
Riad, Thomas S.
Ganjoo, Shonik
Nanez, Selene
Voss, Tiffany
Barsomium, Hampartsum
Welsh, James
Cortez, Maria Angelica
author_sort Duong, Lisa K.
collection PubMed
description Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their importance in cellular functions and their potential as cancer biomarkers have been explored, lipids have yet to be extensively investigated as a possible form of cancer therapy. This review explores the role of lipids in cancer pathophysiology and describes how further understanding of these macromolecules could prompt novel treatments for cancer.
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spelling pubmed-101858322023-05-17 Lipid metabolism in tumor immunology and immunotherapy Duong, Lisa K. Corbali, Halil Ibrahim Riad, Thomas S. Ganjoo, Shonik Nanez, Selene Voss, Tiffany Barsomium, Hampartsum Welsh, James Cortez, Maria Angelica Front Oncol Oncology Lipids are a diverse class of biomolecules that have been implicated in cancer pathophysiology and in an array of immune responses, making them potential targets for improving immune responsiveness. Lipid and lipid oxidation also can affect tumor progression and response to treatment. Although their importance in cellular functions and their potential as cancer biomarkers have been explored, lipids have yet to be extensively investigated as a possible form of cancer therapy. This review explores the role of lipids in cancer pathophysiology and describes how further understanding of these macromolecules could prompt novel treatments for cancer. Frontiers Media S.A. 2023-05-02 /pmc/articles/PMC10185832/ /pubmed/37205182 http://dx.doi.org/10.3389/fonc.2023.1187279 Text en Copyright © 2023 Duong, Corbali, Riad, Ganjoo, Nanez, Voss, Barsomium, Welsh and Cortez https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Duong, Lisa K.
Corbali, Halil Ibrahim
Riad, Thomas S.
Ganjoo, Shonik
Nanez, Selene
Voss, Tiffany
Barsomium, Hampartsum
Welsh, James
Cortez, Maria Angelica
Lipid metabolism in tumor immunology and immunotherapy
title Lipid metabolism in tumor immunology and immunotherapy
title_full Lipid metabolism in tumor immunology and immunotherapy
title_fullStr Lipid metabolism in tumor immunology and immunotherapy
title_full_unstemmed Lipid metabolism in tumor immunology and immunotherapy
title_short Lipid metabolism in tumor immunology and immunotherapy
title_sort lipid metabolism in tumor immunology and immunotherapy
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10185832/
https://www.ncbi.nlm.nih.gov/pubmed/37205182
http://dx.doi.org/10.3389/fonc.2023.1187279
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